大鼠骨髓炎模型。
Model of Osteomyelitis in Rats.
机构信息
G. A. Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia.
出版信息
Bull Exp Biol Med. 2022 Jul;173(3):394-397. doi: 10.1007/s10517-022-05556-6. Epub 2022 Jul 19.
PMID:35852691
Abstract
We developed a rat model of chronic osteomyelitis of the femur caused by Staphylococcus aureus. The clinical, histomorphological, and laboratory signs were compared in rats with osteomyelitis (infected) and control animals receiving saline. On day 21 after infection, clinical, histomorphological, and laboratory signs of chronic osteomyelitis were found in experimental rats.
摘要
我们建立了一个由金黄色葡萄球菌引起的慢性股骨骨髓炎大鼠模型。比较了骨髓炎（感染）大鼠和接受生理盐水的对照动物的临床、组织形态学和实验室指标。在感染后第 21 天，实验大鼠出现了慢性骨髓炎的临床、组织形态学和实验室指标。
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