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1
Aging of the placenta.胎盘老化。
Aging (Albany NY). 2022 Jul 13;14(13):5294-5295. doi: 10.18632/aging.204175.
2
PLACENTAL CALCIFICATION AND MATERNAL AGE.胎盘钙化与母亲年龄
Am J Obstet Gynecol. 1963 Sep 1;87:41-5. doi: 10.1016/s0002-9378(16)35140-7.
3
Effect of maternal age and parity on the risk of uteroplacental bleeding disorders in pregnancy.孕妇年龄和胎次对妊娠期子宫胎盘出血性疾病风险的影响。
Obstet Gynecol. 1996 Oct;88(4 Pt 1):511-6. doi: 10.1016/0029-7844(96)00236-0.
4
Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice.高龄产妇通过降低胎盘炎症细胞因子表达和免疫细胞在小鼠中的积累诱导胎儿生长受限。
J Reprod Dev. 2021 Aug 27;67(4):257-264. doi: 10.1262/jrd.2021-034. Epub 2021 Jun 28.
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PLACENTAL CALCIFICATION A STUDY OF 3,025 SINGLETON AND MULTIPLE PREGNANCIES.胎盘钙化：对3025例单胎和多胎妊娠的研究
J Obstet Gynaecol Br Commonw. 1965 Jun;72:356-73. doi: 10.1111/j.1471-0528.1965.tb01470.x.
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RELATION OF THE MOTHER'S AGE TO OBSTETRIC PERFORMANCE.母亲年龄与产科分娩情况的关系。
Obstet Gynecol. 1964 Sep;24:411-7. doi: 10.1097/00006250-196409000-00014.
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The effect of advanced maternal age on maternal and neonatal outcomes of placenta previa: A register-based cohort study.高龄孕产妇对前置胎盘孕产妇及新生儿结局的影响：一项基于登记处的队列研究。
Eur J Obstet Gynecol Reprod Biol. 2018 Aug;227:1-7. doi: 10.1016/j.ejogrb.2018.05.025. Epub 2018 May 19.
8
Increasing maternal age as a determinant of placenta previa. More important than increasing parity?孕妇年龄增加作为前置胎盘的一个决定因素。比产次增加更重要吗？
J Reprod Med. 1993 Jun;38(6):425-8.
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Effect of maternal age on incidences of apoptotic and proliferative cells in trophoblasts of full-term human placenta.母亲年龄对足月人胎盘滋养层细胞中凋亡和增殖细胞发生率的影响。
Mol Hum Reprod. 2001 Dec;7(12):1179-85. doi: 10.1093/molehr/7.12.1179.
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The impact of advanced maternal age on pregnancy and offspring health: A mechanistic role for placental angiogenic growth mediators.高龄产妇对妊娠和后代健康的影响：胎盘血管生成生长介质的一种机制作用。
Placenta. 2021 Mar;106:15-21. doi: 10.1016/j.placenta.2021.01.024. Epub 2021 Jan 31.
引用本文的文献
1
Cellular senescence: from homeostasis to pathological implications and therapeutic strategies.细胞衰老：从稳态到病理影响及治疗策略
Front Immunol. 2025 Feb 3;16:1534263. doi: 10.3389/fimmu.2025.1534263. eCollection 2025.
2
Thrombotic Alterations under Perinatal Hypoxic Conditions: HIF and Other Hypoxic Markers.围生期缺氧条件下的血栓形成改变：HIF 和其他缺氧标志物。
Int J Mol Sci. 2023 Sep 26;24(19):14541. doi: 10.3390/ijms241914541.
本文引用的文献
1
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions.细胞衰老在女性生殖衰老中的作用及衰老干预治疗的潜力。
Hum Reprod Update. 2022 Feb 28;28(2):172-189. doi: 10.1093/humupd/dmab038.
2
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.高龄相关的 SIRT1 缺乏通过增加波形蛋白乙酰化来损害滋养层上皮-间充质转化。
Aging Cell. 2021 Oct;20(10):e13491. doi: 10.1111/acel.13491. Epub 2021 Oct 3.
3
Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.高龄会导致胎盘提前衰老和畸形，这是通过调节滋养细胞中α-Klotho 的表达来实现的。
Aging Cell. 2021 Jul;20(7):e13417. doi: 10.1111/acel.13417. Epub 2021 Jun 9.
4
Age-related oxidative modifications to uterine albumin impair extravillous trophoblast cells function.与年龄相关的子宫白蛋白氧化修饰损害了绒毛外滋养细胞的功能。
Free Radic Biol Med. 2020 May 20;152:313-322. doi: 10.1016/j.freeradbiomed.2020.03.020. Epub 2020 Mar 26.
5
Advanced maternal age and the impact on maternal and offspring cardiovascular health.高龄产妇及对母婴心血管健康的影响。
Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H387-H394. doi: 10.1152/ajpheart.00045.2019. Epub 2019 Jun 14.
6
N-acetyl-L-cysteine (NAC) delays post-ovulatory oocyte aging in mouse.N-乙酰-L-半胱氨酸（NAC）可延缓小鼠排卵后卵母细胞的老化。
Aging (Albany NY). 2019 Apr 12;11(7):2020-2030. doi: 10.18632/aging.101898.
7
Single-cell reconstruction of the early maternal-fetal interface in humans.人类早期母胎界面的单细胞重建。
Nature. 2018 Nov;563(7731):347-353. doi: 10.1038/s41586-018-0698-6. Epub 2018 Nov 14.
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United we stand not dividing: the syncytiotrophoblast and cell senescence.团结则立，而非分裂：合体滋养层与细胞衰老。
Placenta. 2014 Jun;35(6):341-4. doi: 10.1016/j.placenta.2014.03.012. Epub 2014 Mar 22.
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