Bowman Robin M, Thirunavu Vineeth, Lam Sandi
Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; and.
Department of Neurosurgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
J Neurosurg Case Lessons. 2021 Mar 29;1(13):CASE2011. doi: 10.3171/CASE2011.
Patients with spina bifida have repeated interactions with the healthcare system and often require multiple surgeries throughout their lifetime. Latex precautions are often indicated owing to the high risk of anaphylactic reactions. The choice of dressing for these patients represents an opportunity for learning and standardization if appropriate. The authors discuss the various cases of skin reactions to Mastisol in the literature in comparison with their case and explore the possible mechanisms underlying this skin reaction given the high prevalence of latex allergy in patients with spina bifida.
The authors present the case of a 17-year-old girl with a history of spina bifida and shunted hydrocephalus who underwent a shunt externalization operation and subsequently developed an allergic contact dermatitis reaction to Mastisol liquid adhesive. Topical steroid cream was then administered, and signs and symptoms resolved over the next 3 days.
The choice of dressing should be considered carefully in patients with spina bifida given their repeated exposures and possible sensitivities. The authors aim to increase the awareness of the possibility of Mastisol-induced skin reactions in patients with spina bifida and set a foundation for future studies to investigate the relationship between latex allergy and sensitization to Mastisol.
脊柱裂患者与医疗保健系统有反复接触，且一生中常常需要多次手术。由于过敏反应风险高，通常需要采取乳胶防护措施。为这些患者选择敷料如果恰当，代表着一个学习和标准化的契机。作者将文献中对马替索（Mastisol）发生皮肤反应的各种病例与其病例进行比较，并鉴于脊柱裂患者乳胶过敏的高患病率，探讨这种皮肤反应的潜在机制。
作者报告了一名17岁女孩的病例，该女孩有脊柱裂和分流性脑积水病史，接受了分流外置手术，随后对马替索液体胶粘剂发生了过敏性接触性皮炎反应。随后给予外用类固醇乳膏，症状体征在接下来3天内消退。
鉴于脊柱裂患者反复接触且可能存在敏感性，应为其仔细考虑敷料的选择。作者旨在提高对脊柱裂患者发生马替索诱导皮肤反应可能性的认识，并为未来研究乳胶过敏与对马替索致敏之间的关系奠定基础。
