关于新冠病毒奥密克戎（B.1.1.529）变体的全面综述。

A comprehensive review on Covid-19 Omicron (B.1.1.529) variant.

作者信息

Manjunath R, Gaonkar Santosh L, Saleh Ebraheem Abdu Musad, Husain Kakul

机构信息

Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

Department of Chemistry, Prince Sattam Bin Abdulaziz University, College of Arts and Science, Wadi Al-Dawasir 11991, Saudi Arabia.

出版信息

Saudi J Biol Sci. 2022 Sep;29(9):103372. doi: 10.1016/j.sjbs.2022.103372. Epub 2022 Jul 15.

The world has been combating different variants of SARS-COV-19 since its first outbreak in Wuhan city. SARS-COV-19 is caused by the coronavirus. The corona virus mutates and becomes more transmissible than earlier variants as the day passes. Till 24 November 2021, SARS-COV-19 has four variants Alpha, Beta, Gamma, and Delta, respectively. Among them, the delta variant caused severe havoc across the world. South Africa registered a new variant with the World Health Organization (WHO) on 24 November 2021, which is much more transmissible than previous variants. The WHO classified it as a variant of concern (VOC) on 26 November 2021 and called it the Greek letter Omicron (B.1.1.529), the fifteenth letter in the alphabet. Here a serious attempt was made to comprehend the omicron variant's origin, nomenclature, characteristics, mutations, the difference between delta and omicron variant, epidemiology, transmission, clinical features, impact on immunity, immune evasion, vaccines efficacy, etc.

自新冠病毒在武汉市首次爆发以来，全球一直在与新冠病毒的不同变种作斗争。新冠病毒是由冠状病毒引起的。随着时间的推移，冠状病毒会发生变异，并且变得比早期变种更具传染性。截至2021年11月24日，新冠病毒分别有阿尔法、贝塔、伽马和德尔塔四种变种。其中，德尔塔变种在全球造成了严重破坏。2021年11月24日，南非向世界卫生组织（WHO）报告了一种新变种，它比之前的变种更具传染性。2021年11月26日，世界卫生组织将其列为值得关注的变种（VOC），并将其命名为希腊字母奥密克戎（B.1.1.529），即字母表中的第十五个字母。在此，我们进行了认真的尝试，以了解奥密克戎变种的起源、命名、特征、突变、德尔塔变种与奥密克戎变种的区别、流行病学、传播、临床特征、对免疫的影响、免疫逃逸、疫苗效力等。