Y 染色体在衰老过程中的镶嵌缺失。
Mosaic loss of Y chromosome during aging.
机构信息
Institute of Cardiovascular Regeneration, Goethe University, Frankfurt, Germany.
German Center for Cardiovascular Research DZHK, Partner Site Rhine-Main, Berlin, Germany.
出版信息
Science. 2022 Jul 15;377(6603):266-267. doi: 10.1126/science.add0839. Epub 2022 Jul 14.
PMID:35857599
Abstract
Spread of Y chromosome aneuploidy in myeloid cells with age promotes cardiac fibrosis.
摘要
随着年龄的增长，Y 染色体非整倍体在髓细胞中的扩散促进了心脏纤维化。
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