Rocky Mountain Mental Illness Research, Education, and Clinical Center for Suicide Prevention.
Department of Biostatistics and Informatics.
Psychol Trauma. 2023 Jan;15(1):121-130. doi: 10.1037/tra0001316. Epub 2022 Jul 21.
Bayesian meta-analyses offer several advantages over traditional approaches, including improved accuracy when using a small number of studies and enhanced estimation of heterogeneity. However, psychological trauma research has yet to see widespread adoption of these statistical methods, potentially due to researchers' unfamiliarity with the processes involved. The purpose of this article is to provide a practical tutorial for conducting random-effects Bayesian meta-analyses.
Explanations and recommendations are provided for completing the primary steps of a Bayesian meta-analysis, ranging from model specification to interpretation of results. Furthermore, an illustrative example is used to demonstrate the application of each step. In the example, results are synthesized from six studies included in a previously published systematic review (Holliday et al., 2020), with a combined sample size of 21,244,109, examining the association between posttraumatic stress disorder and risk of suicide in veterans and military personnel.
The posterior distributions for each model estimate, such as the pooled effect size and the heterogeneity parameter, are discussed and interpreted with regard to the probability of increased suicide risk.
Our hope is that this tutorial, along with the provided data and code, facilitate the use of Bayesian meta-analyses in the study of psychological trauma. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
贝叶斯荟萃分析相对于传统方法具有多个优势,包括在使用少量研究时提高准确性和增强对异质性的估计。然而,心理创伤研究尚未广泛采用这些统计方法,这可能是由于研究人员不熟悉相关过程。本文的目的是提供一个实用的教程,用于进行随机效应贝叶斯荟萃分析。
从模型指定到结果解释,为完成贝叶斯荟萃分析的主要步骤提供了说明和建议。此外,还使用一个说明性示例演示了每个步骤的应用。在该示例中,综合了先前发表的系统评价(Holliday 等人,2020)中六项研究的结果,合并样本量为 21244109 例,研究了创伤后应激障碍与退伍军人和军人自杀风险之间的关联。
讨论并解释了每个模型估计的后验分布,例如汇总效应大小和异质性参数,以及与自杀风险增加的概率有关。
我们希望本教程以及提供的数据和代码能够促进贝叶斯荟萃分析在心理创伤研究中的应用。(PsycInfo 数据库记录(c)2023 APA,保留所有权利)。