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接受取栓治疗的缺血性脑卒中患者新发头痛:一项前瞻性研究。

De novo headache in ischemic stroke patients treated with thrombectomy: a prospective study.

机构信息

Services of Neurology and Radiology, University Hospital Marqués de Valdecilla, Universidad de Cantabria and IDIVAL, Av. Valdecilla s/n, 39008, Santander, Cantabria, Spain.

出版信息

J Headache Pain. 2022 Jul 21;23(1):85. doi: 10.1186/s10194-022-01455-3.

DOI:10.1186/s10194-022-01455-3
PMID:35864440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9306161/
Abstract

BACKGROUND AND AIM

Headache attributed to intracranial endovascular procedures is described in the ICHD-3. Our aim was to study the frequency and characteristics of headache specifically related to thrombectomy in patients with ischemic stroke.

METHODS

Prospective evaluation of clinical features of headache after thrombectomy using an ad hoc questionnaire.

RESULTS

One hundred seventeen patients were included (52.1% females). Most had an anterior circulation artery occlusion (91.5%). 93 (79.5%) received general anaesthesia. 111 (94.9%) required stent retriever, 21 (24.4%) angioplasty and 19 (16.2%) aspiration thrombectomy. 31 (26.5%; 95% CI 18.8-35.5%) had headache related to thrombectomy, and it was associated with a history of primary headache (p = 0.004). No differences about sex, initial NIHSS score, or the type or complexity of the procedure were observed. Headache was usually moderate and oppressive, ipsilateral to the artery occlusion and usually lasted less than 48 hours.

CONCLUSIONS

Almost one-third of patients with ischemic stroke who undergo endovascular thrombectomy experience headache in the first 24 hours, occurring more frequently in patients who had a previous history of headaches regardless of the procedure complexity.

摘要

背景与目的

ICHD-3 描述了与颅内血管内操作相关的头痛。我们旨在研究与缺血性卒中患者血管内取栓术相关的头痛的频率和特征。

方法

使用专门的问卷前瞻性评估取栓术后头痛的临床特征。

结果

共纳入 117 例患者(52.1%为女性)。大多数患者为前循环动脉闭塞(91.5%)。93 例(79.5%)接受全身麻醉。111 例(94.9%)需要使用支架取栓器,21 例(24.4%)需要血管成形术,19 例(16.2%)需要抽吸血栓切除术。31 例(26.5%;95%CI 18.8-35.5%)出现与取栓术相关的头痛,且与原发性头痛史相关(p=0.004)。性别、初始 NIHSS 评分或手术类型或复杂性无差异。头痛通常为中度且压迫性,与动脉闭塞同侧,通常持续不到 48 小时。

结论

近三分之一接受血管内取栓术的缺血性卒中患者在术后 24 小时内出现头痛,无论手术复杂性如何,有既往头痛史的患者更常发生头痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5768/9306161/ae89e5cd3564/10194_2022_1455_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5768/9306161/ae89e5cd3564/10194_2022_1455_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5768/9306161/ae89e5cd3564/10194_2022_1455_Fig1_HTML.jpg

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