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探讨身体机能方面男女性别差异:社会人口学、生活方式和健康相关因素如何影响?

Exploring the difference between men and women in physical functioning: How do sociodemographic, lifestyle- and health-related determinants contribute?

机构信息

Department of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.

出版信息

BMC Geriatr. 2022 Jul 22;22(1):610. doi: 10.1186/s12877-022-03216-y.

Abstract

BACKGROUND

To explore whether differences between men and women in the sensitivity to (strength of the association) and/or in the exposure to determinants (prevalence) contribute to the difference in physical functioning, with women reporting more limitations.

METHODS

Data of the Doetinchem Cohort Study was used (n = 5856, initial ages 26-70 years), with follow-up measurements every 5 years (up to 20). Physical functioning (subscale SF-36, range:0-100), sex (men or women) and a number of socio-demographic, lifestyle- and health-related determinants were assessed. Mixed-model multivariable analysis was used to investigate differences between men and women in sensitivity (interaction term with sex) and in exposure (change of the sex difference when adjusting) to determinants of physical functioning.

RESULTS

The physical functioning score among women was 6.55 (95%CI:5.48,7.61) points lower than among men. In general, men and women had similar determinants, but pain was more strongly associated with physical functioning (higher sensitivity), and also more prevalent among women (higher exposure). The higher exposure to low educational level and not having a paid job also contributed to the lower physical functioning score among women. In contrast, current smoking, mental health problems and a low educational level were more strongly associated with a lower physical functioning score among men and lower physical activity and higher BMI were more prevalent among men.

CONCLUSIONS

Although important for physical functioning among both men and women, our findings provide no indications for reducing the difference in physical functioning by promoting a healthy lifestyle but stress the importance of differences in pain, work and education.

摘要

背景

探讨男性和女性在对(关联强度)的敏感性差异和/或在决定因素(流行率)暴露方面的差异是否导致身体功能的差异,女性报告的限制更多。

方法

使用多塞特郡队列研究的数据(n=5856,初始年龄为 26-70 岁),每 5 年(最多 20 年)进行一次随访测量。身体功能(SF-36 子量表,范围:0-100)、性别(男性或女性)以及一些社会人口统计学、生活方式和健康相关决定因素进行了评估。采用混合模型多变量分析来研究男性和女性在敏感性(与性别交互项)和暴露(调整性别差异时的变化)方面对身体功能决定因素的差异。

结果

女性的身体功能评分比男性低 6.55 分(95%CI:5.48,7.61)。一般来说,男性和女性有相似的决定因素,但疼痛与身体功能的关联更强(敏感性更高),而且在女性中更为普遍(暴露度更高)。较低的教育水平和没有带薪工作的更高暴露也导致女性的身体功能评分较低。相比之下,当前吸烟、心理健康问题和较低的教育水平与男性的身体功能评分较低以及男性的身体活动水平较低和 BMI 较高更为相关。

结论

尽管对男性和女性的身体功能都很重要,但我们的研究结果并没有表明通过促进健康的生活方式来缩小身体功能差异,而是强调了疼痛、工作和教育差异的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73a3/9306105/89245fac0019/12877_2022_3216_Fig1_HTML.jpg

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