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生物聚合物类肉瘤样异物肉芽肿:病例报告及文献复习。

Biopolymer sarcoid-like foreign-body granulomas: Case report and literature review.

机构信息

Grupo de Investigación, Universidad CES, Medellín, Colombia.

出版信息

Biomedica. 2022 May 1;42(Sp. 1):8-16. doi: 10.7705/biomedica.6059.

DOI:10.7705/biomedica.6059
PMID:35866725
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9365448/
Abstract

Iatrogenic allogenosis is a disease caused by the injection of biopolymers with esthetic purposes. Clinical manifestations can occur between six hours and 30 years after the procedure with local and/or systemic symptoms. The pathological findings are characterized by the presence of foreign body granulomas with a sarcoid-like reaction. Its interpretation is difficult given its association with sarcoidosis. We report the clinical case of a female patient with granulomatous lesions in reaction to a foreign body secondary to the multiple application of unknown substances on the face and buttocks.

摘要

医源性同种异体病是一种由具有美容目的的生物聚合物注射引起的疾病。临床表现可在治疗后 6 小时至 30 年内发生,伴有局部和/或全身症状。病理表现的特征是存在异物肉芽肿和类肉瘤样反应。由于其与类肉瘤病有关,因此其解释较为困难。我们报告了一例女性患者的临床病例,该患者因面部和臀部多次应用未知物质而出现异物反应性肉芽肿性病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/b00de4cb7285/2590-7379-bio-42-s1-6059-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/01f91f4a2c10/2590-7379-bio-42-s1-6059-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/729044706e01/2590-7379-bio-42-s1-6059-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/b00de4cb7285/2590-7379-bio-42-s1-6059-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/01f91f4a2c10/2590-7379-bio-42-s1-6059-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/729044706e01/2590-7379-bio-42-s1-6059-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/9365448/b00de4cb7285/2590-7379-bio-42-s1-6059-gf3.jpg

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本文引用的文献

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Bacterial antigens and molecular mimicry: the bridging common problematic link in the pathogenesis of sarcoidosis and sarcoid-like reactions: Isn't it time to wake up?细菌抗原与分子模拟:结节病和结节样反应发病机制中常见的关键联系:难道还不该警醒吗?
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Granulomatous foreign-body reaction involving oral and perioral tissues after injection of biomaterials: a series of 7 cases and review of the literature.注射生物材料后累及口腔及口周组织的肉芽肿性异物反应:7例病例系列及文献复习
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A diagnostic trap for the dermatopathologist: granulomatous reactions from cutaneous microimplants for cosmetic purposes.皮肤病理学家的诊断陷阱:用于美容目的的皮肤微植入物引起的肉芽肿反应。
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Treatment of cutaneous sarcoidosis with thalidomide.沙利度胺治疗皮肤结节病
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Treatment of sarcoidosis -- from a basic science point of view.结节病的治疗——从基础科学角度来看
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Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999.结节病声明。美国胸科学会(ATS)、欧洲呼吸学会(ERS)和结节病及其他肉芽肿性疾病世界协会(WASOG)的联合声明,1999年2月经ATS董事会和ERS执行委员会通过。
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Sarcoidosis versus foreign-body granulomas.结节病与异物性肉芽肿
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