Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT; University of Utah School of Medicine, Salt Lake City, UT.
Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT.
Can J Ophthalmol. 2023 Dec;58(6):507-512. doi: 10.1016/j.jcjo.2022.06.015. Epub 2022 Jul 19.
To study the thermal properties and response magnitude of a forced-infusion phacoemulsification machine on 4 ophthalmic viscosurgical devices (OVDs).
Experimental study.
A phacoemulsification tip, thermocouple, and gauge were placed into an artificial anterior chamber with balanced saline solution (BSS) or approximately 0.1 mL of OVD. Once the thermocouple measured a consistent temperature, the pedal was engaged for 60 seconds; then the tip was removed. The machine was cooled for 5 minutes and flushed with BSS to return to baseline. This was repeated 10 times for each OVD. The research consisted of 2 scenarios: vacuum-blocked flow rate and low aspiration flow rate.
All OVDs showed greater temperature changes than BSS. In the vacuum-blocked scenario, these increases were statistically significant. The medium viscosity dispersive OVD (DiscoVisc) reached temperatures exceeding 60°C. In the low-flow scenario, HEALON5 and DisCoVisc were significantly different at 5 seconds and only HEALON5 at 10 seconds. No temperature increases over BSS were greater than 1.0°C.
The dispersive, cohesive, and viscoadaptive OVDs demonstrated higher temperature changes than BSS but did not reach the threshold for corneal incision contracture. The study team verified the need for at least a minimal flow rate before ultrasound, which is especially evident in the first 10 seconds, because a flow rate of only 20 mL/minute mitigated OVD-related thermal effects. Understanding thermal responses enables corneal incision contracture risk reduction.
研究 4 种眼科黏弹剂(OVD)对强制输注超声乳化仪的热性能和反应幅度的影响。
实验研究。
将超声乳化头、热电偶和压力表置于含有平衡盐溶液(BSS)或约 0.1mL OVD 的人工前房内。当热电偶测量到稳定温度时,踩下脚踏板 60 秒;然后取出探头。让机器冷却 5 分钟并用 BSS 冲洗以恢复基线。每种 OVD 重复 10 次。该研究包括 2 种情况:真空阻塞流量和低抽吸流量。
所有 OVD 均比 BSS 引起更大的温度变化。在真空阻塞情况下,这些变化具有统计学意义。中黏度弥散性 OVD(DiscoVisc)的温度超过 60°C。在低流量情况下,HEALON5 和 DisCoVisc 在 5 秒时显著不同,而仅 HEALON5 在 10 秒时显著不同。没有一种 OVD 的温度升高超过 BSS 超过 1.0°C。
弥散性、黏合性和黏弹适应性 OVD 比 BSS 引起更高的温度变化,但未达到角膜切口收缩的阈值。研究小组证实了在进行超声乳化之前至少需要最小流量,这在最初的 10 秒内尤为明显,因为每分钟 20 毫升的流量减轻了 OVD 相关的热效应。了解热反应有助于降低角膜切口收缩的风险。