比较超高剂量率电子束和传输质子束辐照后 HO 的放射分解产物和斑马鱼胚胎的发育。
Comparing radiolytic production of HO and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams.
机构信息
Radiation Oncology Laboratory, Service of Radiation Oncology, Department of Oncology. Lausanne, University Hospital and University of Lausanne, Switzerland.
Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland.
出版信息
Radiother Oncol. 2022 Oct;175:197-202. doi: 10.1016/j.radonc.2022.07.011. Epub 2022 Jul 19.
The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at ≥1400 Gy/s and proton beam at 0.1 and 1260 Gy/s found to be isoefficient at sparing zebrafish embryos.
本文研究了常规和超高剂量率（UHDR）电子和质子束以及常规光子的理化和生物学反应。发现束流的时间结构和性质都会产生影响，在 1400Gy/s 以上的电子束和 0.1Gy/s 与 1260Gy/s 的质子束下，斑马鱼胚胎的剂量相当。
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