St John's Institute of Dermatology, King's College London, London, UK.
Department of Dermatology, Medcin Clinical Research Center, Osasco, SP, Brazil.
Photochem Photobiol Sci. 2022 Nov;21(11):1853-1868. doi: 10.1007/s43630-022-00263-7. Epub 2022 Jul 23.
Public health campaigns advise minimising UV radiation (UVR) exposure to prevent skin cancer and precancer, e.g. actinic keratosis (AK). A 3-day clinical field study, in Brazil, was performed to evaluate the mobile app Sun4Health® by siHealth Ltd. The app performs real-time monitoring of both erythemal and vitamin D-effective solar radiation doses using satellite data, enabling personalised recommendations on optimal sun exposure time and sunscreen use. When coupled to a wearable device, the app also provides body-site specific recommendations ("3D" version). 59 healthy volunteers were randomised into 3 groups, each given a different app providing: (1) ultraviolet index only (control app), (2) personalised recommendations and sun overexposure alerts (Sun4Health® app), (3) as (2) but connected via Bluetooth to a wearable device to monitor sun exposure in 3D (Sun4Health®-3D app). Participants were offered sunscreens (SPF 30 and 50) to use at their discretion. Erythema, quantified by reflectance spectroscopy, was assessed daily in the mornings and evenings on six body sites. Serum vitamin D (25(OH)D) was measured before and after the study. Mean increase of erythema (Mexameter® units ± SD) of all exposed body sites combined over 3 days showed 55.76 ± 47.47 for group 1, 40.27 ± 37.91 for group 2 and 37.12 ± 30.69 for group 3 (p < 0.05 for all groups). Mean increase of serum 25(OH)D (nmol/l ± SD) showed 1.32 ± 36.49 for group 1, 6.38 ± 21.19 for group 2 and 18.68 ± 35.45 for group 3 (p > 0.05 for all groups). The results show that the Sun4Health® app is safe to use and can modify behaviour to reduce skin erythema (sunburn) yet not decreasing vitamin D status.
公共卫生运动建议尽量减少紫外线（UVR）暴露，以预防皮肤癌和癌前病变，例如光化性角化病（AK）。在巴西进行了一项为期 3 天的临床现场研究，以评估 siHealth Ltd. 的移动应用程序 Sun4Health®。该应用程序使用卫星数据实时监测红斑和维生素 D 有效太阳辐射剂量，能够针对最佳日晒时间和防晒霜使用提供个性化建议。当与可穿戴设备结合使用时，该应用程序还提供特定于身体部位的建议（“3D”版本）。59 名健康志愿者被随机分为 3 组，每组使用不同的应用程序：（1）仅紫外线指数（对照应用程序），（2）个性化建议和太阳过度暴露警报（Sun4Health®应用程序），（3）如（2），但通过蓝牙连接到可穿戴设备以监测 3D 中的太阳暴露（Sun4Health®-3D 应用程序）。参与者可以自行选择使用防晒霜（SPF30 和 50）。使用反射光谱法每天早上和晚上在六个身体部位评估红斑。在研究前后测量血清维生素 D（25（OH）D）。3 天内所有暴露部位的红斑平均增加量（Mexameter®单位±SD）显示第 1 组为 55.76±47.47，第 2 组为 40.27±37.91，第 3 组为 37.12±30.69（所有组均 p<0.05）。血清 25（OH）D 平均增加量（nmol/l±SD）显示第 1 组为 1.32±36.49，第 2 组为 6.38±21.19，第 3 组为 18.68±35.45（所有组均 p>0.05）。结果表明，Sun4Health®应用程序安全使用，并能改变行为以减少皮肤红斑（晒伤），而不会降低维生素 D 水平。
