Ghaemian Naser, Ghadimi Reza, Soraya Soraya, Mouodi Simin
Cancer Research Center, Babol University of Medical Sciences, Babol, Iran.
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Caspian J Intern Med. 2022;13(Suppl 3):187-192. doi: 10.22088/cjim.13.0.187.
When the first wave of COVID-19 outbreak occurred, the infrastructure for definitive detection of the disease through real-time polymerase chain reaction (RT-PCR) was not yet available in many regions, and a large proportion of suspected patients were inevitably referred to radiology centers to provide a chest CT scan. This research was conducted to describe chest CT characteristics in patients who underwent chest CT during the first weeks of COVID-19 outbreak in Babol, Iran.
All non-hospitalized suspected COVID-19 patients referred to the state radiologic clinic to perform chest CT from March 8, 2020 to March 28, 2020 have been enrolled in this observational study. All CT scans were reviewed by a faculty member radiologist with approximately 20 years of experience.
Totally, 2,207 (52.3%) men and 2016 (47.7%) women have been examined. Imaging characteristics in 2292 (54.3%) individuals illustrated a highly suggestive sign of COVID-19 infection while 1869 (44.3%) had a normal chest CT scan. 1813 cases (77.00%) had bilateral involvement and 541 cases (23.00%) were infected unilaterally; Also, 1727 (73.36%) patients had left-sided involvement. Lung field involvement in 2036 (86.49%) patients was less than 20%. Ground glass opacity had a sensitivity, specificity, PPV, NPV, LR+ and LR- of 99%, 96%, 96%, 98%, 22 and 0.01, respectively, for categorization of a patient as a COVID-19 case. These values were 99%, 73%, 70%, 99%, 3.72% and 0.01%, respectively for consolidations.
Although, RT-PCR is still introduced as the gold standard method for definite diagnosis, diagnostic accuracy of chest CT in COVID-19 detection is considerable.
在新型冠状病毒肺炎（COVID-19）疫情第一波爆发时，许多地区尚无通过实时聚合酶链反应（RT-PCR）进行该病确诊检测的基础设施，很大一部分疑似患者不可避免地被转诊至放射科进行胸部CT扫描。本研究旨在描述伊朗巴博勒在COVID-19疫情爆发最初几周内接受胸部CT检查的患者的胸部CT特征。
本观察性研究纳入了2020年3月8日至2020年3月28日转诊至国家放射诊所进行胸部CT检查的所有非住院疑似COVID-19患者。所有CT扫描均由一位有大约20年经验的放射科教员进行阅片。
共检查了2207名男性（52.3%）和2016名女性（47.7%）。2292名个体（54.3%）的影像学特征显示出高度提示COVID-19感染的征象，而1869名个体（44.3%）的胸部CT扫描结果正常。1813例（77.00%）为双侧受累，541例（23.00%）为单侧感染；此外，1727例（73.36%）患者左侧受累。2036例（86.49%）患者的肺野受累面积小于20%。磨玻璃影将患者分类为COVID-19病例的敏感度、特异度、阳性预测值、阴性预测值、阳性似然比和阴性似然比分别为99%、96%、96%、98%、22和0.01。实变的这些值分别为99%、73%、70%、99%、3.72%和0.01%。
虽然RT-PCR仍然是确诊的金标准方法，但胸部CT在COVID-19检测中的诊断准确性相当可观。
