连接黏附分子：动脉粥样硬化中的潜在蛋白质
Junctional Adhesion Molecules: Potential Proteins in Atherosclerosis.
作者信息
Wang Junqi, Chen Xiaoping
机构信息
Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, China.
出版信息
Front Cardiovasc Med. 2022 Jul 7;9:888818. doi: 10.3389/fcvm.2022.888818. eCollection 2022.
Junctional adhesion molecules (JAMs) are cell-cell adhesion molecules of the immunoglobulin superfamily and are involved in the regulation of diverse atherosclerosis-related processes such as endothelial barrier maintenance, leucocytes transendothelial migration, and angiogenesis. To combine and further broaden related results, this review concluded the recent progress in the roles of JAMs and predicted future studies of JAMs in the development of atherosclerosis.
连接黏附分子（JAMs）是免疫球蛋白超家族的细胞间黏附分子，参与多种与动脉粥样硬化相关过程的调节，如内皮屏障维持、白细胞跨内皮迁移和血管生成。为了整合并进一步拓宽相关研究成果，本综述总结了JAMs作用方面的最新进展，并预测了JAMs在动脉粥样硬化发展研究中的未来方向。
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