全国老年人群样本中的吸烟状况与认知功能
Smoking Status and Cognitive Function in a National Sample of Older Adults.
作者信息
Zhang Qiaoyang, Zhang Min, Chen Yun, Zhu Shumin, Zhou Wang, Zhang Lihao, Dong Guanzhong, Cao Yin
机构信息
Department of Psychology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, China.
Department of Neurology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, China.
出版信息
Front Psychiatry. 2022 Jul 6;13:926708. doi: 10.3389/fpsyt.2022.926708. eCollection 2022.
AIMS
To examine the correlation between smoking status and different domains of cognitive function in elderly Americans.
METHODS
We used data from the 2011 to 2014 U.S. National Health and Nutrition Examination Survey (NHANES). Participants over 60 years with available smoking history and cognitive function data were enrolled in our analysis. The NHANES study included the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) assessment, the Animal Fluency Test (AFT), and the Digit Symbol Substitution Test (DSST) to assess cognition. Multivariate regression analyses were used to estimate the association between cigarette smoking and cognitive function.
RESULTS
A total of 2,932 participants were enrolled in the analysis, including 372 (12.7%) current smokers, 1,115 (38%) former smokers, and 1,445 (49.3%) never smokers. Never smokers had in average 3.82 (95% CI, 2.21 to 5.43) points more than current smokers in the DSST, whereas former smokers had 3.12 (95% CI, 1.51 to 4.73) points more than current smokers. Besides, smoking was not associated with the results of the AFT or the CERAD test.
CONCLUSIONS
This study suggests that cigarette smoking is associated with processing speed among the American elderly.
目的
研究美国老年人吸烟状况与不同认知功能领域之间的相关性。
方法
我们使用了2011年至2014年美国国家健康与营养检查调查（NHANES）的数据。纳入分析的是60岁以上有可用吸烟史和认知功能数据的参与者。NHANES研究包括阿尔茨海默病注册协会（CERAD）评估、动物流畅性测试（AFT）和数字符号替换测试（DSST）以评估认知。采用多变量回归分析来估计吸烟与认知功能之间的关联。
结果
共有2932名参与者纳入分析，其中包括372名（12.7%）当前吸烟者、1115名（38%）既往吸烟者和1445名（49.3%）从不吸烟者。在数字符号替换测试中，从不吸烟者平均比当前吸烟者多3.82分（95%置信区间，2.21至5.43），而既往吸烟者比当前吸烟者多3.12分（95%置信区间，1.51至4.73）。此外，吸烟与动物流畅性测试或CERAD测试结果无关。
结论
本研究表明，在美国老年人中，吸烟与处理速度有关。
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