Chauhan Sanjaya, Srivastava Manoj K, Pathak Anklesh K
Department of Pharmacology Narayana Hrudayalaya Allied Health Sciences Bangalore Karnataka India.
Department of Psychiatry Om Surgical Centre and Maternity Centre Varanasi Uttar Pradesh India.
Health Sci Rep. 2022 Jul 20;5(4):e741. doi: 10.1002/hsr2.741. eCollection 2022 Jul.
In Ayurveda, ashwagandha is a popular plant for promoting youthful energy, longevity, and overall well-being. It is also an excellent aphrodisiac herb that aids in the improvement and maintenance of normal sexual health. The present study aims to evaluate the effect of ashwagandha root extract on improving sexual health in adult males.
In this 8-week randomized, double-blind, placebo-controlled study, we investigated the aphrodisiac property of an ashwagandha root extract in adult males. Fifty participants with lower sexual desire were randomly allocated to take 300 mg of ashwagandha root extract or placebo capsules twice daily. Outcomes were measured using the derogatis interview for sexual functioning-male (DISF-M) questionnaire, serum testosterone, serum prolactin, and short-form survey-36 quality of life questionnaire before and after the intervention.
Compared to placebo, ashwagandha root extract supplementation was associated with a statistically significant increase in the total DISF-M scores (mean difference -9.8; 95% confidence interval, -10.73 to -8.87; < 0.0001; -test). It was also associated with a statistically significant increase in serum testosterone levels (-66.52; -80.70 to -52.34; < 0.0001; -test). However, the prolactin level did not change after intervention in both the ashwagandha and placebo groups (-1.06; -2.78 to 0.66; > 0.05).
These findings suggest that ashwagandha demonstrated a significant subjective perception of sexual well-being and assisted in increasing serum testosterone levels in the participants.
在阿育吠陀医学中，南非醉茄是一种广受欢迎的植物，可促进青春活力、延年益寿并提升整体健康水平。它也是一种出色的壮阳草药，有助于改善和维持正常的性健康。本研究旨在评估南非醉茄根提取物对成年男性性健康的改善作用。
在这项为期8周的随机、双盲、安慰剂对照研究中，我们调查了南非醉茄根提取物对成年男性的壮阳特性。50名性欲较低的参与者被随机分配，每天两次服用300毫克南非醉茄根提取物胶囊或安慰剂胶囊。在干预前后，使用男性性功能德罗加蒂斯访谈问卷（DISF-M）、血清睾酮、血清催乳素和简短健康调查-36生活质量问卷来测量结果。
与安慰剂相比，补充南非醉茄根提取物与DISF-M总分在统计学上显著增加相关（平均差异-9.8；95%置信区间，-10.73至-8.87；P<0.0001；t检验）。它还与血清睾酮水平在统计学上显著增加相关（-66.52；-80.70至-52.34；P<0.0001；t检验）。然而，在南非醉茄组和安慰剂组中，干预后催乳素水平均未改变（-1.06；-2.78至0.66；P>0.05）。
这些发现表明，南非醉茄在参与者中表现出对性健康的显著主观感受，并有助于提高血清睾酮水平。
