Kang Soonpil, Nashar Sharbel, Masud Arif
Graduate research assistant, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
John and Eileen Blumenschein Professor. Department of Civil and Environmental Engineering - Grainger College of Engineering, and Department of Translational and Biomedical Sciences - Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Extreme Mech Lett. 2022 Jul;54. doi: 10.1016/j.eml.2022.101684. Epub 2022 Mar 14.
A stabilized FSI method is presented for coupling shear-rate dependent model of blood with finitely deforming anisotropic hyperelastic model of arteries. The blood-artery coupling conditions are weakly enforced to accommodate non-matching blood-artery meshes which provides great flexibility in independent discretization of fluid and solid subdomains in the patient-specific geometric models. The variationally derived interface coupling terms play an important role in the concurrent solution of the nonlinear mixed-field problem across non-matching discretizations. Two test cases are presented that investigate the effect of growth of aortic aneurysm on local changes in blood flow and stress concentrations in calcified arteries under pulsating flows to highlight the clinical relevance of the proposed method for cardiovascular applications.
提出了一种稳定的流固相互作用（FSI）方法，用于将依赖剪切率的血液模型与动脉的有限变形各向异性超弹性模型相耦合。血液-动脉耦合条件以弱强制方式施加，以适应不匹配的血液-动脉网格，这为在患者特定几何模型中独立离散流体和固体子域提供了极大的灵活性。通过变分推导得到的界面耦合项在跨不匹配离散化的非线性混合场问题的并行求解中起着重要作用。给出了两个测试案例，研究了主动脉瘤生长对脉动流作用下钙化动脉局部血流变化和应力集中的影响，以突出所提出方法在心血管应用中的临床相关性。
