Holmes Clifton J, Granados Andrea
Program in Physical Therapy, Washington University of Medicine, St. Louis, Missouri.
Department of Pediatrics, Division of Pediatric Endocrinology and Diabetes, Washington University of Medicine, St. Louis, Missouri.
Strength Cond J. 2022 Feb;44(1):111-118. doi: 10.1519/ssc.0000000000000641. Epub 2021 Apr 27.
Cystic fibrosis (CF) is the most prevalent hereditary life-threatening disease in the Caucasian population. With the improvement in clinical care, individuals with CF are living longer, and CF-related diabetes (CFRD) has emerged as a major complication. The diagnosis of CFRD is associated with shortening survival, increasing morbidity, worsening physical capacity, and body composition. Engagement in exercise training has become a prominent nonpharmacologic intervention that aims to improve fitness and clinical outcomes in individuals with CF and CFRD. This column will specifically focus on the potential benefits of resistance training and provide recommendations for children and adolescents with CF and CFRD.
囊性纤维化（CF）是白种人群中最常见的遗传性危及生命的疾病。随着临床护理水平的提高，CF患者的寿命延长，而CF相关糖尿病（CFRD）已成为一种主要并发症。CFRD的诊断与生存期缩短、发病率增加、身体能力恶化和身体成分改变有关。进行运动训练已成为一项重要的非药物干预措施，旨在改善CF和CFRD患者的健康状况和临床结局。本专栏将特别关注抗阻训练的潜在益处，并为患有CF和CFRD的儿童和青少年提供建议。
