Blaschke Katja, Hellmich Martin, Samel Christina, Listl Stefan, Schubert Ingrid
PMV Research Group, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
Institute of Medical Statistics and Computational Biology (IMSB), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
Dent J (Basel). 2022 Jul 13;10(7):133. doi: 10.3390/dj10070133.
There is empirical evidence of an association between periodontitis and coronary heart disease (CHD). However, it is uncertain whether periodontal treatment in CHD patients might lead to reduced healthcare costs. This study aims to assess the association between periodontal treatment and healthcare costs in newly diagnosed CHD patients. Data from 21,263 adults who were continuously insured between 2011 and 2016 and who were newly diagnosed with CHD in 2013 were selected from a German claims database. The study population was differentiated by the utilization of periodontal treatment. The average treatment effect (ATE) of periodontal treatment on healthcare costs (total, inpatient, outpatient, drugs) was investigated using weighted Poisson regression models conditional on covariates and is shown as a ratio (of geometric means). Periodontal treatment was documented for 4.7% of the persons in the study population. Newly diagnosed CHD patients showed an ATE of 0.98 for total healthcare cost (95% CI 0.90-1.06), 0.79 for inpatient costs (95% CI 0.61-1.04), and 0.95 for drug costs (95% CI 0.87-1.04). A statistically significant 7% increase in outpatient costs was shown (95% CI 1.01-1.13). Despite a lack of statistical significance in most cases, the study provides evidence of a meaningful decrease in inpatient costs after periodontal treatment. Further studies are needed.
有经验证据表明牙周炎与冠心病（CHD）之间存在关联。然而，冠心病患者接受牙周治疗是否会降低医疗成本尚不确定。本研究旨在评估新诊断的冠心病患者牙周治疗与医疗成本之间的关联。从德国理赔数据库中选取了2011年至2016年持续参保且于2013年新诊断为冠心病的21263名成年人的数据。研究人群根据牙周治疗的使用情况进行区分。使用基于协变量的加权泊松回归模型研究牙周治疗对医疗成本（总计、住院、门诊、药物）的平均治疗效果（ATE），并以（几何均值的）比率表示。研究人群中有4.7%的人记录了牙周治疗情况。新诊断的冠心病患者的总医疗成本ATE为0.98（95%CI 0.90 - 1.06），住院成本ATE为0.79（95%CI 0.61 - 1.04），药物成本ATE为0.95（95%CI 0.87 - 1.04）。门诊成本显示有统计学意义的7%的增加（95%CI 1.01 - 1.13）。尽管在大多数情况下缺乏统计学意义，但该研究提供了牙周治疗后住院成本有显著降低的证据。还需要进一步的研究。
