Queensland Brain Institute, University of Queensland, St Lucia, QLD 4072, Australia.
Life Sciences Institute and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
Curr Biol. 2022 Jul 25;32(14):R788-R790. doi: 10.1016/j.cub.2022.06.021.
Corollary discharge allows organisms to discriminate external sensory inputs from self-generated cues. However, the underlying synaptic and molecular mechanisms are not well understood. A new study has identified a tyraminergic corollary discharge signal that extrasynaptically modulates chemosensory neurons in Caenorhabditis elegans.
侧支放电使生物体能够区分外部感觉输入和自身产生的线索。然而,其潜在的突触和分子机制尚不清楚。一项新的研究已经确定了一种酪胺能侧支放电信号,该信号可以在 Caenorhabditis elegans 的化学感觉神经元的突触外调节。