School of Chemistry and Chemical Engineering, Qinghai Minzu University, Xining, 810007, Qinghai, China.
College of Chemical Engineering, North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Sci Rep. 2022 Jul 26;12(1):12759. doi: 10.1038/s41598-022-17066-6.
This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The results show that when the axial diameter ratio is 1:2, the elastic modulus of the scaffold is about 1.25 and the yield strength is about 1.36. The scaffold's longitudinal and transverse mechanical properties align with human bone tissue. Its permeability is also better than that of circular pores. The scaffold with an axial diameter ratio of 1:3 has the best permeability, ranging from 1.28e-8 to 1.60e-8 m, which is more conducive to the adsorption of cells on the inner wall of the scaffold. These results show that the scaffold structure with an axial diameter ratio of not 1:1 has more advantages than the ordinary uniform scaffold structure with an axial diameter ratio of 1:1. This is of great significance to the optimal design of scaffold.
本文通过数值模拟和实验，综合评价了不同轴径比的原始三周期极小曲面钛 6 铝 4 钒仿生支架的静态力学压缩性能、渗透性和细胞黏附对内壁的影响。结果表明，当轴径比为 1:2 时，支架的弹性模量约为 1.25，屈服强度约为 1.36。支架的纵向和横向力学性能与人骨组织相匹配。其渗透性也优于圆形孔。轴径比为 1:3 的支架具有最佳的渗透性，范围为 1.28e-8 至 1.60e-8 m，更有利于细胞在内壁上的吸附。这些结果表明，与轴径比为 1:1 的普通均匀支架结构相比，轴径比不为 1:1 的支架结构具有更多的优势。这对支架的优化设计具有重要意义。
