Suppr超能文献

遗忘型轻度认知障碍(aMCI)和阿尔茨海默病性痴呆(ADD)中的情景记忆:使用“门与人物”工具区分早期aMCI-晚期aMCI-轻度ADD诊断组。

Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer's Disease Dementia (ADD): Using the "Doors and People" Tool to Differentiate between Early aMCI-Late aMCI-Mild ADD Diagnostic Groups.

作者信息

Chatzikostopoulos Athanasios, Moraitou Despina, Tsolaki Magdalini, Masoura Elvira, Papantoniou Georgia, Sofologi Maria, Papaliagkas Vasileios, Kougioumtzis Georgios, Papatzikis Efthymios

机构信息

Neurosciences and Neurodegenerative Diseases, Postgraduate Course, Medical School, Faculty of Health Sciences, Aristotle University, 54124 Thessaloniki, Greece.

Greek Association of Alzheimer's Disease and Related Disorders (GAADRD), 54643 Thessaloniki, Greece.

出版信息

Diagnostics (Basel). 2022 Jul 21;12(7):1768. doi: 10.3390/diagnostics12071768.

Abstract

Episodic memory is the type of memory that allows the recollection of personal experiences containing information on what has happened and, also, where and when it happened. Because of its sensitivity to neurodegenerative diseases and the aging of the brain, it is considered a hallmark of Alzheimer's disease dementia (ADD). The objective of the present study was to examine episodic memory in amnestic mild cognitive impairment (aMCI) and ADD. Patients with the diagnosis of early aMCI, late aMCI, and mild ADD were evaluated using the Doors and People tool which consists of four subtests examining different aspects of episodic memory. The statistical analysis with receiver operating characteristic curves (ROC) showed the discriminant potential and the cutoffs of every subtest. Overall, the evaluation of episodic memory with the Doors and People tool can discriminate with great sensitivity between the different groups of people with AD and, especially, early aMCI, late aMCI, and mild ADD patients.

摘要

情景记忆是一种能够回忆个人经历的记忆类型,这些经历包含了发生了什么事情的信息,以及事情发生的地点和时间。由于其对神经退行性疾病和大脑衰老的敏感性,它被认为是阿尔茨海默病性痴呆(ADD)的一个标志。本研究的目的是检查遗忘型轻度认知障碍(aMCI)和ADD中的情景记忆。使用“门与人物”工具对诊断为早期aMCI、晚期aMCI和轻度ADD的患者进行评估,该工具由四个子测试组成,用于检查情景记忆的不同方面。采用受试者工作特征曲线(ROC)进行统计分析,显示了每个子测试的判别潜力和临界值。总体而言,使用“门与人物”工具对情景记忆进行评估,可以高度敏感地区分不同组别的AD患者,特别是早期aMCI、晚期aMCI和轻度ADD患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51a0/9324962/595933c2cdf1/diagnostics-12-01768-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验