Sîrbu Carmen Adella, Stefan Ion, Dumitru Rodica, Mitrica Marian, Manole Aida Mihaela, Vasile Titus Mihai, Stefani Constantin, Ranetti Aurelian Emil
Department of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
Department of Infectious Diseases, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
Healthcare (Basel). 2022 Jun 23;10(7):1170. doi: 10.3390/healthcare10071170.
Air pollution is a real public health problem, it being one of the five most common causes of mortality in developing countries. However, pollution studies have focused on the cardiovascular and pulmonary systems in recent decades. Recently, researchers have moved towards a new direction, tracing a direct link between pollution and stroke. Stroke has many known risk factors such as smoking, a sedentary lifestyle, and hypertension. Pollution is universally widespread, already a matter of public interest, so that, although intuitive, it is difficult to connect the two. The particles found in the air that we breathe, regardless of their origin, can attack the body in different ways, causing inflammation, and triggering a true cascade of phenomena that end up attacking the central nervous system and other organs. This article tries to explain the series of phenomena that determine the harmful effect of particles present in the air, with an increased focus on the central nervous system and especially on strokes. A deeper understanding of these phenomena helps in guiding future studies and finding viable solutions to protect people at risk.
空气污染是一个切实存在的公共卫生问题，它是发展中国家最常见的五大死因之一。然而，近几十年来，污染研究主要集中在心血管和肺部系统。最近，研究人员转向了一个新方向，探寻污染与中风之间的直接联系。中风有许多已知的风险因素，如吸烟、久坐不动的生活方式和高血压。污染普遍存在，已经是公众关注的问题，所以，尽管直观，但很难将两者联系起来。我们呼吸的空气中发现的颗粒物，无论其来源如何，都能以不同方式攻击身体，引发炎症，并触发一系列最终会攻击中枢神经系统和其他器官的现象。本文试图解释决定空气中颗粒物有害影响的一系列现象，尤其关注中枢神经系统，特别是中风。对这些现象的更深入理解有助于指导未来的研究，并找到可行的解决方案来保护高危人群。
