Second Department of Internal Medicine, ″Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Department of Oncology, ″Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Medicina (Kaunas). 2022 Jul 14;58(7):932. doi: 10.3390/medicina58070932.
Given the increased incidence of colorectal cancer worldwide, especially in developed and developing countries, is comes as no surprise that researchers are concentrating on methods to combat this public health issue, through investigating both lifestyle interventions and treatment options. Although treatment options are being constantly discovered and developed, researchers have also begun investigating the influence that nutrition and lifestyle have on CRC. Among the food categories, nuts and seeds boast numerous beneficial effects for cardiovascular health and metabolic balance and they contain a plethora of phytochemicals and antioxidants. The present narrative review aims to offer a broad perspective to date on the known effects of this consumption on colorectal cancer. For this purpose, articles were identified by conducting a search in the PubMed and Google Scholar databases, using search phrases such as ″nut intake and colorectal cancer″ and ″seed consumption and colorectal cancer", narrowing the search pool to those articles published between 2019 and 2022. The search returned eight relevant papers, all of which were validated by a second author. While the existing research is divided between those studies which have found no significant link between nut consumption and colorectal cancer protection and those which have, there is a consensus regarding the necessity for further research on this subject, as well as the possible mechanisms which might be involved in the protective effect observed by some researchers.
鉴于全世界结直肠癌的发病率上升，特别是在发达国家和发展中国家，研究人员专注于通过研究生活方式干预和治疗选择来解决这一公共卫生问题也就不足为奇了。虽然不断发现和开发新的治疗选择，但研究人员也开始研究营养和生活方式对 CRC 的影响。在食物类别中，坚果和种子对心血管健康和代谢平衡有许多有益的影响，它们含有大量的植物化学物质和抗氧化剂。本综述旨在提供迄今为止关于这种消费对结直肠癌影响的广泛视角。为此，通过在 PubMed 和 Google Scholar 数据库中使用“nut intake and colorectal cancer”和“seed consumption and colorectal cancer”等搜索短语进行搜索，确定了文章，并将搜索范围缩小到 2019 年至 2022 年期间发表的文章。搜索返回了八篇相关文章，所有文章都由第二位作者进行了验证。虽然现有的研究在坚果消费与结直肠癌保护之间没有显著关联的研究和有显著关联的研究之间存在分歧，但人们一致认为需要对这一主题进行进一步研究，以及一些研究人员观察到的保护作用可能涉及的潜在机制。
