Institute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.
Division of Biological Sciences and Health, University of Sonora, Hermosillo 83000, Mexico.
Medicina (Kaunas). 2022 Jul 18;58(7):948. doi: 10.3390/medicina58070948.
: Multiple sclerosis (MS) is a disease that manifests with varied neurological symptoms, including muscle weakness, especially in the lower extremities. Strength exercises play an important role in the rehabilitation and functional maintenance of these patients. The individualized prescription of strength exercises is recommended to be based on the maximum force determined by the one-repetition maximum (1RM), although to save time and because it requires less equipment, it is often determined by the maximum voluntary isometric contraction (MVIC). The purpose of this work was to study, in patients with MS (pwMS), the reliability of MVIC and the correlation between the MVIC and 1RM of the knee extensors and to predict the MVIC-based 1RM. A total of 328 pwMS participated. The study of the reliability of MVIC included all pwMS, for which MVIC was determined twice in one session. Their 1RM was also evaluated. The sample was randomized by MS type, sex, and neurological disability score into a training group and a testing group for the analysis of the correlation and prediction of MVIC-based 1RM. : MVIC repeatability (ICC, 2.1 = 0.973) was determined, along with a minimum detectable change of 13.2 kg. The correlation between MVIC and 1RM was R = 0.804, with a standard error estimate of 12.2 kg. The absolute percentage error of 1RM prediction based on MVIC in the test group was 12.7%, independent of MS type and with no correlation with neurological disability score. In patients with MS, MVIC presents very good intrasubject repeatability, and the difference between two measurements of the same subject must differ by 17% to be considered a true change in MVIC. There is a high correlation between MVIC and 1RM, which allows estimation of 1RM once MVIC is known, with an estimation error of about 12%, regardless of sex or type of MS, and regardless of the degree of neurological disability.
: 多发性硬化症 (MS) 是一种表现出多种神经症状的疾病，包括肌肉无力，尤其是下肢无力。力量训练在这些患者的康复和功能维持中起着重要作用。建议根据 1 次最大重复次数 (1RM) 确定的最大力量为这些患者制定个性化的力量训练处方，尽管为了节省时间并且因为它需要较少的设备，通常根据最大自主等长收缩 (MVIC) 来确定。这项工作的目的是研究多发性硬化症患者 (pwMS) 中 MVIC 的可靠性，以及 MVIC 与膝关节伸肌 1RM 的相关性，并预测基于 MVIC 的 1RM。共有 328 名 pwMS 参与了这项研究。MVIC 可靠性的研究包括所有 pwMS，他们在一次会议中两次确定 MVIC。还评估了他们的 1RM。根据 MS 类型、性别和神经残疾评分，对样本进行随机分组，分为训练组和测试组，用于分析基于 MVIC 的 1RM 的相关性和预测。: MVIC 重复性（ICC，2.1 = 0.973）得到确定，最小可检测变化为 13.2 公斤。MVIC 与 1RM 之间的相关性为 R = 0.804，标准误差估计值为 12.2 公斤。基于 MVIC 在测试组中预测 1RM 的绝对百分比误差为 12.7%，与 MS 类型无关，与神经残疾评分也无相关性。在多发性硬化症患者中，MVIC 呈现出非常好的个体内重复性，同一受试者两次测量的差异必须相差 17%，才能被认为是 MVIC 的真正变化。MVIC 与 1RM 之间存在高度相关性，因此一旦知道 MVIC，就可以估计 1RM，估计误差约为 12%，无论性别或 MS 类型如何，也无论神经残疾程度如何。
