Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine & Key Laboratory of State Administration of Traditional Chinese Medicine for Agarwood Sustainable Utilization, Hainan Branch of the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Haikou 570311, China.
Molecules. 2022 Jul 15;27(14):4528. doi: 10.3390/molecules27144528.
As a valuable medicinal herb and spice, agarwood is widely used in the fields of daily chemistry, traditional medicine, religion and literary collection. It mainly contains sesquiterpenes and 2-(2-phenylethyl)chromones, which are often used to soothe the body and mind, relieve anxiety, act as an antidepressant and treat insomnia and other mental disorders, presenting a good calming effect. This paper reviews the chemical composition of the essential oils of different sources of agarwood, as well as the progress of research on the sedative and tranquilizing pharmacological activity and mechanism of action of agarwood essential oil (AEO), and then analyzes the current problems of AEO research and its application prospects in the treatment of mental diseases.
作为一种有价值的药用植物和香料，沉香在日用化工、传统医学、宗教和文学收藏等领域有着广泛的应用。它主要含有倍半萜和 2-(2-苯乙基)色酮，经常用于舒缓身心、缓解焦虑、作为抗抑郁药和治疗失眠和其他精神障碍，呈现出良好的镇静效果。本文综述了不同来源沉香精油的化学成分，以及沉香精油（AEO）镇静和安定药理学活性和作用机制的研究进展，然后分析了 AEO 研究的现状及其在精神疾病治疗中的应用前景。
