• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新型茁霉多糖水凝胶的合成与流变学表征

Synthesis and Rheological Characterization of a Novel Salecan Hydrogel.

作者信息

Zhang Qinling, Ren Teng, Gan Jing, Sun Lirong, Guan Chenxia, Zhang Qian, Pan Shihui, Chen Hao

机构信息

Marine College, Shandong University (Weihai), No. 180 Wenhua West Road, Gao Strict, Weihai 264209, China.

College of Life Sciences, Yantai University, No. 30 Qingquan Road, Laishan Strict, Yantai 264000, China.

出版信息

Pharmaceutics. 2022 Jul 18;14(7):1492. doi: 10.3390/pharmaceutics14071492.

DOI:10.3390/pharmaceutics14071492
PMID:35890387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9323046/
Abstract

Salecan (Sal) is a novel microbial polysaccharide. In the present research, thermal treatment was performed to fabricate Sal hydrogel. The effect of Sal concentration on water holding capacity, swelling properties, texture properties, and microstructure of the hydrogels was discussed. It was found that the equilibrium degree of swelling (EDS) of Sal hydrogels was above 1500%, inferred Sal was a highly hydrophilic polysaccharide. As Sal concentration increased from 3.5 to 8.0 wt%, the hardness increased from 0.88 to 2.07 N and the water hold capability (WHC) increased from 91.3% to 98.2%. Furthermore, the internal network structure of Sal hydrogel also became denser and more uniform. Rheological studies suggested that elastic hydrogel formed under the gelation process. All these results demonstrated that Sal hydrogel prepared by thermal treatment had good gelling properties, which opened up a new safe way for the preparation of Sal hydrogel and broadened the application range of Sal.

摘要

茁霉多糖(Salecan,简称Sal)是一种新型微生物多糖。在本研究中,通过热处理制备了Sal水凝胶。探讨了Sal浓度对水凝胶保水能力、溶胀特性、质地特性及微观结构的影响。结果发现,Sal水凝胶的平衡溶胀度(EDS)高于1500%,表明Sal是一种高度亲水性多糖。随着Sal浓度从3.5 wt%增加到8.0 wt%,硬度从0.88 N增加到2.07 N,保水能力(WHC)从91.3%增加到98.2%。此外,Sal水凝胶的内部网络结构也变得更加致密和均匀。流变学研究表明,在凝胶化过程中形成了弹性水凝胶。所有这些结果表明,通过热处理制备的Sal水凝胶具有良好的凝胶特性,为Sal水凝胶的制备开辟了一条新的安全途径,并拓宽了Sal的应用范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/e2f1138ea8de/pharmaceutics-14-01492-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/e322cf28bebd/pharmaceutics-14-01492-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/6e8dab7bf8d5/pharmaceutics-14-01492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/bcaed53db771/pharmaceutics-14-01492-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/eea0e93b2a8e/pharmaceutics-14-01492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/acf3d321dd72/pharmaceutics-14-01492-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/5206d1aa42a4/pharmaceutics-14-01492-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/79dc7be948ed/pharmaceutics-14-01492-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/4dcb05733a6c/pharmaceutics-14-01492-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/e2f1138ea8de/pharmaceutics-14-01492-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/e322cf28bebd/pharmaceutics-14-01492-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/6e8dab7bf8d5/pharmaceutics-14-01492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/bcaed53db771/pharmaceutics-14-01492-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/eea0e93b2a8e/pharmaceutics-14-01492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/acf3d321dd72/pharmaceutics-14-01492-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/5206d1aa42a4/pharmaceutics-14-01492-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/79dc7be948ed/pharmaceutics-14-01492-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/4dcb05733a6c/pharmaceutics-14-01492-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b915/9323046/e2f1138ea8de/pharmaceutics-14-01492-g008.jpg

相似文献

1
Synthesis and Rheological Characterization of a Novel Salecan Hydrogel.新型茁霉多糖水凝胶的合成与流变学表征
Pharmaceutics. 2022 Jul 18;14(7):1492. doi: 10.3390/pharmaceutics14071492.
2
Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.热诱导和转谷氨酰胺酶制备和性质的 salecan-大豆分离蛋白复合水凝胶。
Int J Mol Sci. 2022 Aug 20;23(16):9383. doi: 10.3390/ijms23169383.
3
Preparation and characterization of a novel pH-sensitive Salecan-g-poly(acrylic acid) hydrogel for controlled release of doxorubicin.用于阿霉素控释的新型pH敏感型莎来聚糖接枝聚丙烯酸水凝胶的制备与表征
J Mater Chem B. 2015 Apr 7;3(13):2685-2697. doi: 10.1039/c5tb00264h. Epub 2015 Feb 26.
4
Synthesis and characterization of a novel pH-thermo dual responsive hydrogel based on salecan and poly(N,N-diethylacrylamide-co-methacrylic acid).基于可得然胶和聚(N,N-二乙基丙烯酰胺-共-甲基丙烯酸)的新型pH-温度双响应水凝胶的合成与表征
Colloids Surf B Biointerfaces. 2015 Dec 1;136:1182-92. doi: 10.1016/j.colsurfb.2015.11.007. Epub 2015 Nov 7.
5
A novel thermo-responsive hydrogel based on salecan and poly(N-isopropylacrylamide): synthesis and characterization.基于沙菜聚糖和聚(N-异丙基丙烯酰胺)的新型温敏水凝胶:合成与表征。
Colloids Surf B Biointerfaces. 2015 Jan 1;125:1-11. doi: 10.1016/j.colsurfb.2014.10.057. Epub 2014 Nov 13.
6
Synthesis and characterization of a novel semi-IPN hydrogel based on Salecan and poly(N,N-dimethylacrylamide-co-2-hydroxyethyl methacrylate).基于沙利聚糖和聚(N,N-二甲基丙烯酰胺-co-2-羟乙基甲基丙烯酸酯)的新型半互穿网络水凝胶的合成与表征。
Carbohydr Polym. 2014 May 25;105:135-44. doi: 10.1016/j.carbpol.2014.01.051. Epub 2014 Feb 4.
7
Investigation of Salecan/poly(vinyl alcohol) hydrogels prepared by freeze/thaw method.通过冻融法制备 Salecan/聚乙烯醇水凝胶的研究。
Carbohydr Polym. 2015 Mar 15;118:60-9. doi: 10.1016/j.carbpol.2014.11.021. Epub 2014 Nov 20.
8
Novel Green Crosslinked Salecan Hydrogels and Preliminary Investigation of Their Use in 3D Printing.新型绿色交联的沙雷菌多糖水凝胶及其在3D打印中的应用初步研究
Pharmaceutics. 2023 Jan 21;15(2):373. doi: 10.3390/pharmaceutics15020373.
9
Synthesis and characterization of a novel hydrogel: salecan/polyacrylamide semi-IPN hydrogel with a desirable pore structure.一种新型水凝胶的合成与表征:具有理想孔结构的可得然胶/聚丙烯酰胺半互穿网络水凝胶
J Mater Chem B. 2014 Jun 21;2(23):3646-3658. doi: 10.1039/c3tb21711f. Epub 2014 May 9.
10
Facile formation of salecan/agarose hydrogels with tunable structural properties for cell culture.易于制备具有可调结构特性的 salecan/琼脂糖水凝胶用于细胞培养。
Carbohydr Polym. 2019 Nov 15;224:115208. doi: 10.1016/j.carbpol.2019.115208. Epub 2019 Aug 17.

引用本文的文献

1
Research on the application of biomaterial-based responsive hydrogels in the tumor microenvironment.基于生物材料的响应性水凝胶在肿瘤微环境中的应用研究
PeerJ. 2025 Jul 8;13:e19609. doi: 10.7717/peerj.19609. eCollection 2025.
2
Performance Characterization and Antibacterial Activity of a Composite Hydrogel Composed of Oxidized κ-Carrageenan, Acrylamide, and Silver-Based Metal-Organic Frameworks.由氧化κ-卡拉胶、丙烯酰胺和银基金属有机框架组成的复合水凝胶的性能表征及抗菌活性
Gels. 2025 May 29;11(6):407. doi: 10.3390/gels11060407.
3
Gelatin-Oxidized Alginate and Chitosan-Coated Zein Nanoparticle Hydrogel Composite to Enhance Breast Cancer Cytotoxicity in Dual-Drug Delivery.

本文引用的文献

1
Cognition of polysaccharides from confusion to clarity: when the next "omic" will come?多糖认知:从混沌到清晰——下一个“组学”何时到来?
Crit Rev Food Sci Nutr. 2023;63(20):4728-4743. doi: 10.1080/10408398.2021.2007045. Epub 2021 Nov 30.
2
Fabrication of fish gelatin / sodium alginate double network gels for encapsulation of probiotics.鱼明胶/海藻酸钠双网络凝胶的制备及其用于益生菌的包埋。
J Sci Food Agric. 2021 Aug 15;101(10):4398-4408. doi: 10.1002/jsfa.11081. Epub 2021 Jan 26.
3
Salecan-Clay Based Polymer Nanocomposites for Chemotherapeutic Drug Delivery Systems; Characterization and In Vitro Biocompatibility Studies.
明胶-氧化海藻酸盐和壳聚糖包被的玉米醇溶蛋白纳米颗粒水凝胶复合材料用于增强双药递送中的乳腺癌细胞毒性
ACS Omega. 2024 Oct 31;9(45):45190-45202. doi: 10.1021/acsomega.4c06404. eCollection 2024 Nov 12.
4
The Recent Progress of the Cellulose-Based Antibacterial Hydrogel.基于纤维素的抗菌水凝胶的最新进展
Gels. 2024 Jan 29;10(2):109. doi: 10.3390/gels10020109.
5
Novel Green Crosslinked Salecan Hydrogels and Preliminary Investigation of Their Use in 3D Printing.新型绿色交联的沙雷菌多糖水凝胶及其在3D打印中的应用初步研究
Pharmaceutics. 2023 Jan 21;15(2):373. doi: 10.3390/pharmaceutics15020373.
6
Novel Nanocomposite Hydrogels Based on Crosslinked Microbial Polysaccharide as Potential Bioactive Wound Dressings.基于交联微生物多糖的新型纳米复合水凝胶作为潜在的生物活性伤口敷料
Materials (Basel). 2023 Jan 20;16(3):982. doi: 10.3390/ma16030982.
7
Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.热诱导和转谷氨酰胺酶制备和性质的 salecan-大豆分离蛋白复合水凝胶。
Int J Mol Sci. 2022 Aug 20;23(16):9383. doi: 10.3390/ijms23169383.
用于化疗药物递送系统的基于凝结多糖-黏土的聚合物纳米复合材料;表征及体外生物相容性研究
Materials (Basel). 2020 Nov 27;13(23):5389. doi: 10.3390/ma13235389.
4
A novel biocompatible double network hydrogel consisting of konjac glucomannan with high mechanical strength and ability to be freely shaped.一种新型的生物相容性双网络水凝胶,由具有高机械强度和可自由成型能力的魔芋葡甘聚糖组成。
J Mater Chem B. 2015 Mar 7;3(9):1769-1778. doi: 10.1039/c4tb01653j. Epub 2015 Jan 22.
5
Salecan polysaccharide-based hydrogels and their applications: a review.基于 Salecan 多糖的水凝胶及其应用:综述。
J Mater Chem B. 2019 Apr 28;7(16):2577-2587. doi: 10.1039/c8tb03312a. Epub 2019 Mar 20.
6
Biocompatible Hydrogels Based on Food Gums with Tunable Physicochemical Properties as Scaffolds for Cell Culture.基于具有可调理化性质的食用胶的生物相容性水凝胶作为细胞培养的支架。
J Agric Food Chem. 2020 Mar 25;68(12):3770-3778. doi: 10.1021/acs.jafc.9b06120. Epub 2020 Feb 27.
7
Formation of self-assembled polyelectrolyte complex hydrogel derived from salecan and chitosan for sustained release of Vitamin C.基于沙莱糖和壳聚糖的自组装聚电解质复合水凝胶的形成及其用于维生素 C 的缓释。
Carbohydr Polym. 2020 Apr 15;234:115920. doi: 10.1016/j.carbpol.2020.115920. Epub 2020 Feb 3.
8
Enhanced properties of injectable chitosan-based thermogelling hydrogels by silk fibroin and longan seed extract for bone tissue engineering.丝素蛋白和龙眼籽提取物增强壳聚糖基温敏水凝胶的性能用于骨组织工程。
Int J Biol Macromol. 2019 Oct 1;138:412-424. doi: 10.1016/j.ijbiomac.2019.07.100. Epub 2019 Jul 16.
9
Development of Self-Healing Double-Network Hydrogels: Enhancement of the Strength of Wheat Gluten Hydrogels by In Situ Metal-Catechol Coordination.自修复双网络水凝胶的研制:原位金属-儿茶酚配位增强小麦面筋水凝胶的强度。
J Agric Food Chem. 2019 Jun 12;67(23):6508-6516. doi: 10.1021/acs.jafc.9b01649. Epub 2019 May 31.
10
Development of chitosan-poly(ethyleneimine) based double network cryogels and their application as superadsorbents for phosphate.壳聚糖-聚乙烯亚胺基双网络冷冻凝胶的制备及其作为超吸磷剂的应用。
Carbohydr Polym. 2019 Apr 15;210:17-25. doi: 10.1016/j.carbpol.2019.01.054. Epub 2019 Jan 17.