Imipenem Resistance in Gram-Negative Bacteria in the Central Pediatric Teaching Hospital in Baghdad, Iraq.

Antimicrobial resistance (AMR) is a serious challenge for infectious disease prevention and treatment, according to the World Health Organization. It is a worldwide problem caused primarily by inappropriate and insufficient therapy, misuse of antimicrobials without physician supervision, unnecessary hospital readmissions, and other factors. AMR has several consequences, including increased medical costs and mortality. The present study aimed to evaluate imipenem resistance in gram-negative bacteria in Central Pediatric Teaching Hospital in Baghdad, Iraq, and determine this bacteria resistance in different samples. Initially, a total of 100 different samples were collected from child patients from October 1, 2020, to August 31, 2021. Each isolate was identified using VITEK 2 automated microbiology system. The recorded data showed that the isolated organisms resistant to imipenem included (n=21), (n=19), and (n=16). In the current study, was the most common pathogen in males (n=57) compared to female (n=43), followed by and , particularly in the age range of 1 day- 3 years. Depending on the sample type, , the most imipenem-resistant bacteria, was found more in the urine of patients with urinary tract infections. was equally found in blood, urine, wound swab, and sputum samples. In comparison to other samples, was found in greater numbers in the blood and in an equal number in urine and cerebrospinal.