Madouros Nikolaos, Jarvis Sommer, Saleem Amber, Koumadoraki Evgenia, Sharif Shayka, Khan Safeera
Surgery, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Anatomy/Cell Biology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus. 2022 Jun 21;14(6):e26149. doi: 10.7759/cureus.26149. eCollection 2022 Jun.
Chronic obstructive pulmonary disease (COPD) is one of the most common diseases worldwide with its prevalence increasing with age. It is commonly comorbid with other diseases and managing patients could be difficult and expensive. Chronic kidney disease (CKD) is often present in COPD patients and may be underdiagnosed, especially if it is mild. This study intended to summarize recent findings showing the correlation between the two diseases. Studies were gathered that were published in the last 11 years, from 2010 to 2021. PubMed was used as the main source of data, but papers from the references of the included other sources were added for thoroughness. Observational studies on examining the prevalence and prognosis of comorbid COPD and CKD published in the English language were included. A higher prevalence of CKD in COPD patients was found in most studies; it was found that a higher risk of mortality is present if these diseases coexist. Further research is required and more extensive prospective studies are needed with matched control groups to support the correlation.
慢性阻塞性肺疾病（COPD）是全球最常见的疾病之一，其患病率随年龄增长而增加。它常与其他疾病合并存在，治疗患者可能既困难又昂贵。慢性肾脏病（CKD）在COPD患者中很常见，可能未得到充分诊断，尤其是在病情较轻时。本研究旨在总结近期显示这两种疾病之间相关性的研究结果。收集了2010年至2021年这11年间发表的研究。PubMed被用作主要数据来源，但为了全面性，也添加了纳入研究的参考文献中的其他来源的论文。纳入了以英文发表的关于COPD和CKD合并症患病率及预后的观察性研究。大多数研究发现COPD患者中CKD的患病率较高；发现这两种疾病共存时死亡风险更高。需要进一步研究，并且需要更广泛的前瞻性研究及匹配的对照组来支持这种相关性。
