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草药导致免疫功能正常患者的声门上区真菌与细菌合并感染

Fungal and Bacterial Co-infection of Supraglottis in an Immunocompetent Patient Secondary to Herbal Medicine.

作者信息

Zulkaflay Muhammad Sallehin, Mat Baki Marina

机构信息

Otolaryngology - Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Otolaryngology - Head and Neck Surgery, Hospital Melaka, Melaka, MYS.

出版信息

Cureus. 2022 Jun 21;14(6):e26181. doi: 10.7759/cureus.26181. eCollection 2022 Jun.

Abstract

Fungal infections are among the major infections among immunocompromised patients. They are becoming more common with the widespread use of antibiotics, steroid therapy, and the increasing number of immunocompromised patients. However, the incidence of laryngeal fungal and bacterial co-infection has rarely been reported. As same as laryngeal fungal infection, it mimics other types of laryngeal disease such as gastroesophageal reflux disease, granulomatous disease, and malignant lesions. There is a high likelihood of misdiagnosis, leading to delayed treatment and morbidity from fungal and bacterial co-infection of the larynx. A high index of suspicion is required to make the diagnosis and one should look for evidence of immunosuppression and predisposing factors to local mucosal barrier impairment. However, herbal medicine is a rare cause. We present a case of fungal and bacterial co-infection of supraglottis in an immunocompetent patient secondary to herbal medicine.

摘要

真菌感染是免疫功能低下患者的主要感染之一。随着抗生素、类固醇疗法的广泛使用以及免疫功能低下患者数量的增加,真菌感染正变得越来越普遍。然而,喉真菌和细菌合并感染的发生率鲜有报道。与喉真菌感染一样,它会模仿其他类型的喉部疾病,如胃食管反流病、肉芽肿性疾病和恶性病变。误诊的可能性很高,导致喉真菌和细菌合并感染的治疗延误和发病。需要高度怀疑指数才能做出诊断,并且应该寻找免疫抑制的证据以及局部黏膜屏障受损的诱发因素。然而,草药是一种罕见的病因。我们报告一例免疫功能正常的患者因草药导致声门上区真菌和细菌合并感染的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa53/9304684/c999bfa19fbc/cureus-0014-00000026181-i01.jpg

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