Khalid Nabeeha, Patel Pragnesh D, Alghareeb Rahmah, Hussain Afshan, Maheshwari Marvi V
Cardiology, Omar Hospital and Cardiac Centre, Lahore, PAK.
Research, St. George's University School of Medicine, St. George's, GRD.
Cureus. 2022 Jun 21;14(6):e26178. doi: 10.7759/cureus.26178. eCollection 2022 Jun.
Sepsis remains a worldwide challenge for physicians with many patients admitted to ICUs with septic shock. Septic shock management involves targeted treatment to control infections, reduce end-organ damage, and reverse the injury. Sepsis-induced myocardial dysfunction or septic cardiomyopathy remains an avenue to be explored with regard to underlying pathophysiology and definite treatment guidelines. This article has compiled various studies to explain the possible mechanisms involved in the development of septic cardiomyopathy and the existing diagnostic criteria including radiological and laboratory tests to assess septic cardiomyopathy. Furthermore, the article highlights management options currently available for physicians dealing with myocardial dysfunction secondary to sepsis.
脓毒症仍然是全球医生面临的挑战，许多患有脓毒性休克的患者被收入重症监护病房。脓毒性休克的管理包括针对性治疗，以控制感染、减少终末器官损伤并逆转损伤。脓毒症诱导的心肌功能障碍或脓毒性心肌病在潜在病理生理学和明确治疗指南方面仍是有待探索的领域。本文汇总了各项研究，以解释脓毒性心肌病发生过程中可能涉及的机制以及现有的诊断标准，包括用于评估脓毒性心肌病的影像学和实验室检查。此外，本文还重点介绍了目前可供处理脓毒症继发心肌功能障碍的医生选择的管理方法。
