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接种 SARS-CoV-2 mRNA 疫苗后出现妊娠类天疱疮样皮疹。

Pseudo-Pemphigoid Gestationis Eruption Following SARS-CoV-2 Vaccination with mRNA Vaccine.

作者信息

de Lorenzi Caroline, Kaya Gürkan, Toutous Trellu Laurence

机构信息

Department of Dermatology and Venereology, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, CH-1205 Geneva, Switzerland.

Department of Clinical Pathology, Geneva University Hospitals, CH-1205 Geneva, Switzerland.

出版信息

Dermatopathology (Basel). 2022 Jun 24;9(3):203-206. doi: 10.3390/dermatopathology9030025.

DOI:10.3390/dermatopathology9030025
PMID:35892478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9326618/
Abstract

Auto-immune reactions, including auto-immune bullous disease, have been reported following SARS-CoV-2 virus vaccination. Few cases of bullous pemphigoid are described, but there has been no case of pemphigoid gestationis. We report the first case here.

摘要

据报道,接种严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫苗后会出现自身免疫反应,包括自身免疫性大疱性疾病。仅有少数大疱性类天疱疮病例的描述,但妊娠类天疱疮尚无病例报道。我们在此报告首例病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e8/9326618/3a3d78b44af6/dermatopathology-09-00025-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e8/9326618/b88b38499e71/dermatopathology-09-00025-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e8/9326618/3a3d78b44af6/dermatopathology-09-00025-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e8/9326618/b88b38499e71/dermatopathology-09-00025-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e8/9326618/3a3d78b44af6/dermatopathology-09-00025-g002.jpg

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1
Pseudo-Pemphigoid Gestationis Eruption Following SARS-CoV-2 Vaccination with mRNA Vaccine.接种 SARS-CoV-2 mRNA 疫苗后出现妊娠类天疱疮样皮疹。
Dermatopathology (Basel). 2022 Jun 24;9(3):203-206. doi: 10.3390/dermatopathology9030025.
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Infantile Bullous Pemphigoid: Vaccination and SARS-CoV-2 Infection as Triggers.婴儿大疱性类天疱疮:疫苗接种和新冠病毒感染作为触发因素
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[Pemphigoid gestationis: treatment by topical class I corticosteroid].妊娠类天疱疮:外用I类皮质类固醇治疗
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[Differential diagnosis of bullous skin lesions in neonates: pemphigoid gestationis].
Z Geburtshilfe Neonatol. 2004 Dec;208(6):236-8. doi: 10.1055/s-2004-835871.
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A severe persistent case of pemphigoid gestationis treated with intravenous immunoglobulins and cyclosporin.一例采用静脉注射免疫球蛋白和环孢素治疗的重症持续性妊娠类天疱疮病例。
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本文引用的文献

1
Autoimmune Bullous Dermatosis Following COVID-19 Vaccination: A Series of Five Cases.新冠疫苗接种后自身免疫性大疱性皮肤病:五例病例系列
Cureus. 2022 Mar 13;14(3):e23127. doi: 10.7759/cureus.23127. eCollection 2022 Mar.
2
Case Report: Circulating Anti-SARS-CoV-2 Antibodies Do Not Cross-React With Pemphigus or Pemphigoid Autoantigens.病例报告:循环抗SARS-CoV-2抗体与天疱疮或类天疱疮自身抗原无交叉反应。
Front Med (Lausanne). 2021 Dec 20;8:807711. doi: 10.3389/fmed.2021.807711. eCollection 2021.
3
Autoreactivity to BP180 Neoepitopes in Patients With Pemphigoid Gestationis.
妊娠疱疹患者中 BP180 新表位的自身反应性。
JAMA Dermatol. 2022 Feb 1;158(2):212-214. doi: 10.1001/jamadermatol.2021.5294.
4
Bullous pemphigoid in a young male after COVID-19 mRNA vaccine: a report and brief literature review.一名年轻男性在接种新冠病毒mRNA疫苗后发生大疱性类天疱疮:病例报告及文献简要综述
J Eur Acad Dermatol Venereol. 2022 Apr;36(4):e257-e259. doi: 10.1111/jdv.17891. Epub 2021 Dec 30.
5
Bullous pemphigoid induced by the AstraZeneca COVID-19 vaccine.阿斯利康新冠疫苗诱发的大疱性类天疱疮。
Ann Dermatol Venereol. 2022 Mar;149(1):56-57. doi: 10.1016/j.annder.2021.07.008. Epub 2021 Sep 30.
6
Bullous drug eruption after second dose of mRNA-1273 (Moderna) COVID-19 vaccine: Case report.第二剂mRNA-1273(Moderna)新冠疫苗接种后出现大疱性药疹:病例报告
J Infect Public Health. 2021 Oct;14(10):1392-1394. doi: 10.1016/j.jiph.2021.06.021. Epub 2021 Jul 8.
7
Clinical and histopathological spectrum of delayed adverse cutaneous reactions following COVID-19 vaccination.接种 COVID-19 疫苗后迟发性皮肤不良反应的临床和组织病理学谱。
J Cutan Pathol. 2022 Jan;49(1):34-41. doi: 10.1111/cup.14104. Epub 2021 Aug 8.
8
Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases.报告的 Moderna 和辉瑞 COVID-19 疫苗接种后皮肤反应:基于登记的 414 例病例研究。
J Am Acad Dermatol. 2021 Jul;85(1):46-55. doi: 10.1016/j.jaad.2021.03.092. Epub 2021 Apr 7.
9
Updated international expert recommendations for the management of autoimmune bullous diseases during the COVID-19 pandemic.新型冠状病毒肺炎大流行期间自身免疫性大疱性疾病管理的最新国际专家建议。
J Eur Acad Dermatol Venereol. 2021 Jul;35(7):e412-e414. doi: 10.1111/jdv.17207. Epub 2021 Mar 19.
10
Review of autoimmune blistering diseases: the Pemphigoid diseases.自身免疫性水疱性疾病综述:大疱性类天疱疮。
J Eur Acad Dermatol Venereol. 2019 Sep;33(9):1685-1694. doi: 10.1111/jdv.15679. Epub 2019 Jul 11.