Sánchez de la Nava Ana María, Gómez-Cid Lidia, Ríos-Muñoz Gonzalo Ricardo, Fernández-Santos María Eugenia, Fernández Ana I, Arenal Ángel, Sanz-Ruiz Ricardo, Grigorian-Shamagian Lilian, Atienza Felipe, Fernández-Avilés Francisco
Department of Cardiology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares, CIBERCV, 28029 Madrid, Spain.
BioTech (Basel). 2022 Jun 30;11(3):23. doi: 10.3390/biotech11030023.
Translational science has been introduced as the nexus among the scientific and the clinical field, which allows researchers to provide and demonstrate that the evidence-based research can connect the gaps present between basic and clinical levels. This type of research has played a major role in the field of cardiovascular diseases, where the main objective has been to identify and transfer potential treatments identified at preclinical stages into clinical practice. This transfer has been enhanced by the intromission of digital health solutions into both basic research and clinical scenarios. This review aimed to identify and summarize the most important translational advances in the last years in the cardiovascular field together with the potential challenges that still remain in basic research, clinical scenarios, and regulatory agencies.
转化科学已被引入作为科学领域与临床领域之间的纽带，它使研究人员能够提供并证明循证研究可以弥合基础水平与临床水平之间存在的差距。这类研究在心血管疾病领域发挥了重要作用，其主要目标是识别并将临床前阶段确定的潜在治疗方法转化为临床实践。数字健康解决方案融入基础研究和临床场景，进一步推动了这种转化。本综述旨在识别并总结近年来心血管领域最重要的转化进展，以及基础研究、临床场景和监管机构中仍然存在的潜在挑战。
