Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark.
Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
BMC Infect Dis. 2018 Mar 13;18(1):127. doi: 10.1186/s12879-018-3030-z.
The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease complex is unknown.
As part of two cross-sectional studies on human and porcine cysticercosis in the area, unique epidemiological and cost data were collected in Angónia district, Mozambique in 2007. These data provided the basis for the assessment of the societal cost of T. solium in the district, which estimates the impact of the disease on human and pig populations and includes both health and economic approaches in the analysis.
Approximately 0.7% (95% Uncertainty Interval (UI), 0.4-0.9) and 0.4% (95% UI, 0.2-0.6) of the total population in the district was estimated to suffer from neurocysticercosis (NCC)-associated epilepsy and headache. The estimated average number of disability-adjusted life years (DALYs) due to NCC-associated epilepsy and headache was 6 (95% UI, 4-8) per thousand persons per year. The total annual costs due to T. solium cysticercosis were estimated at 90,000 USD (95% UI, 39,483-201,463) of which 72% (95% UI, 45-91) were costs linked to human cysticercosis and 28% (95% UI, 9.5-55) to pig production losses. The annual economic burden per NCC-associated epilepsy case in the district amounted to 33 USD (95% UI, 10-76).
In this highly endemic area of Mozambique a large number of individuals suffer from symptoms associated with NCC. Healthy years of life are lost and people are left living with disabilities. Infected pork poses a serious risk to the community and affects the economy of smallholder farmers. Cost for treatment and hospitalization of patients with NCC-associated epilepsy, and lack of productivity and inability of suffering patients to work, further hinder socioeconomic development. Feasible solutions framed within a country specific algorithm and stepwise approaches are needed to control the parasite in the country.
在莫桑比克太特省昂戈尼亚地区，动物源寄生虫猪带绦虫流行，但其疾病负担尚不明确。
作为该地区人类和猪囊尾蚴的两项横断面研究的一部分，2007 年在莫桑比克昂戈尼亚区收集了独特的流行病学和成本数据。这些数据为评估该地区猪带绦虫的社会成本提供了依据，该评估考虑了疾病对人类和猪群的影响，并在分析中纳入了健康和经济方法。
据估计，该地区约有 0.7%（95%不确定区间（UI），0.4-0.9）和 0.4%（95% UI，0.2-0.6）的总人口患有与神经囊虫病（NCC）相关的癫痫和头痛。因 NCC 相关癫痫和头痛导致的残疾调整生命年（DALY）估计平均为每年每千人 6 人（95% UI，4-8）。由于猪带绦虫囊尾蚴病造成的年总成本估计为 9 万美元（95% UI，3.9483-20.1463 万美元），其中 72%（95% UI，45-91%）与人类囊虫病相关成本有关，28%（95% UI，9.5-55%）与猪生产损失有关。该地区每例 NCC 相关癫痫病例的年经济负担为 33 美元（95% UI，10-76 美元）。
在莫桑比克这个高度流行地区，许多人患有与囊虫病相关的症状。健康的生命年数减少，人们生活在残疾中。受感染的猪肉对社区构成严重威胁，影响小农的经济。治疗和住院治疗 NCC 相关癫痫患者的费用，以及生产力的丧失和患病患者无法工作，进一步阻碍了社会经济的发展。需要制定符合国情的算法和逐步方法的可行解决方案，以控制该国的寄生虫。
