Akinyemi Kabiru O, Fakorede Christopher O, Amisu Kehinde O, Wareth Gamal
Department of Microbiology, Lagos State University, Km 15, Badagry Expressway, P.O. Box 0001, Lasu Post Office, Ojo, Lagos 102101, Nigeria.
Friedrich-Loeffler-Institut, (FLI), Institute of Bacterial Infections and Zoonoses, Naumburger Str. 96a, 07743 Jena, Germany.
Vet Sci. 2022 Jul 26;9(8):384. doi: 10.3390/vetsci9080384.
The global burden of human and animal brucellosis remains enormous. The disease, which is endemic in Nigeria, lacks appropriate attention and national data. This review estimated the burden and distribution of human and animal brucellosis in Nigeria in the last twenty years (2001-2021). Publications reporting the detection of brucellosis in Nigeria were sorted from different search engines, including PubMed, ResearchGate, Scopus, and Google Scholar, to generate data on its prevalence, spatial distribution, and predisposing factors. The results of the national seroprevalence of human and animal brucellosis as revealed in this study were 17.6% (554/3144) and 13.3% (8547/64,435), respectively. Specifically, 15.8% (7178/45,363) seroprevalence of brucellosis was recorded in northern Nigeria as against 8.7% (1902/21,740) seroprevalence in the southern part. It also indicated that 78.7% of the detected brucellae were un-typed. The species detected were (15.2%), (4%), (1.8%), and (0.4%). This study revealed that brucellosis is endemic in Nigeria. Culture and molecular methods for detecting brucellosis and reports on antimicrobial susceptibility testing remain a conjecture. This review will help researchers redirect their research focus and serve as a guide for policymakers on measures for managing brucellosis in Nigeria.
人类和动物布鲁氏菌病的全球负担仍然巨大。这种在尼日利亚流行的疾病缺乏应有的关注和国家数据。本综述估计了过去二十年（2001 - 2021年）尼日利亚人类和动物布鲁氏菌病的负担及分布情况。从不同的搜索引擎，包括PubMed、ResearchGate、Scopus和谷歌学术搜索中筛选出报告在尼日利亚检测到布鲁氏菌病的出版物，以生成有关其流行率、空间分布和诱发因素的数据。本研究揭示的人类和动物布鲁氏菌病的全国血清阳性率结果分别为17.6%（554/3144）和13.3%（8547/64435）。具体而言，尼日利亚北部布鲁氏菌病的血清阳性率为15.8%（7178/45363），而南部为8.7%（1902/21740）。研究还表明，检测到的布鲁氏菌中有78.7%未分型。检测到的菌种有 （15.2%）、 （4%）、 （1.8%）和 （0.4%）。本研究表明布鲁氏菌病在尼日利亚呈地方性流行。用于检测布鲁氏菌病的培养和分子方法以及抗菌药物敏感性测试的报告仍不确定。本综述将有助于研究人员重新调整研究重点，并为政策制定者提供有关尼日利亚布鲁氏菌病管理措施的指导。
