Shkalim Zemer Vered, Grossman Zachi, Cohen Herman Avner, Hoshen Moshe, Gerstein Maya, Yosef Noga, Cohen Moriya, Ashkenazi Shai
Dan-Petach Tikva District, Clalit Health Services, Petach Tikva 4972339, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Vaccines (Basel). 2022 Jul 22;10(8):1167. doi: 10.3390/vaccines10081167.
We aimed to examine rates of COVID-19 vaccination to elucidate the need for targeted public health interventions. We retrospectively reviewed the electronic medical files of all adults registered in a central district in Israel from 1 January 2021 to 31 March 2022. The population was characterized by vaccination status against COVID-19 and the number of doses received. Univariate and multivariable analyses were used to identify predictors of low vaccination rates that required targeted interventions. Of the 246,543 subjects included in the study, 207,911 (84.3%) were vaccinated. The minority groups of ultra-Orthodox Jews and Arabs had lower vaccination rates than the non-ultra-Orthodox Jews (68.7%, 80.5% and 87.7%, respectively, p < 0.001). Adults of low socioeconomic status (SES) had lower vaccination rates compared to those of high SES (74.4% vs. 90.8%, p < 0.001). Adults aged 20−59 years had a lower vaccination rate than those ≥60 years (80.0% vs. 92.1%, p < 0.0001). Multivariate analysis identified five independent variables that were significantly (p < 0.001) associated with low vaccination rates: minority groups of the ultra-Orthodox sector and Arab population, and underlying conditions of asthma, smoking and diabetes mellitus (odds ratios: 0.484, 0.453, 0.843, 0.901 and 0.929, respectively). Specific targeted public health interventions towards these subpopulations with significantly lower rates of vaccination are suggested.
我们旨在研究新冠病毒疫苗接种率，以阐明针对性公共卫生干预措施的必要性。我们回顾性分析了2021年1月1日至2022年3月31日在以色列一个中心地区登记的所有成年人的电子病历。研究对象的特征为新冠病毒疫苗接种状况及接种剂量数。采用单因素和多因素分析来确定需要针对性干预的低接种率预测因素。在纳入研究的246,543名受试者中，207,911人（84.3%）接种了疫苗。极端正统派犹太人和阿拉伯少数群体的接种率低于非极端正统派犹太人（分别为68.7%、80.5%和87.7%，p<0.001）。社会经济地位低的成年人的接种率低于社会经济地位高的成年人（74.4%对90.8%，p<0.001）。20至59岁的成年人的接种率低于60岁及以上的成年人（80.0%对92.1%，p<0.0001）。多因素分析确定了五个与低接种率显著相关（p<0.001）的独立变量：极端正统派部门和阿拉伯人口的少数群体，以及哮喘、吸烟和糖尿病等基础疾病（优势比分别为：0.484、0.453、0.843、0.901和0.929）。建议针对这些接种率显著较低的亚人群采取特定的针对性公共卫生干预措施。
