Division of Rheumatology, Department of Internal Medicine, Istanbul University-Cerrahpasa, School of Medicine, Istanbul, and Behçet's Disease Research Centre, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
Clin Exp Rheumatol. 2022 Sep;40(8):1461-1471. doi: 10.55563/clinexprheumatol/h4dkrs. Epub 2022 Jul 26.
This review highlights publications on different aspects of Behçet's syndrome (BS) that appeared in 2021 and provides a critical view. These publications include works on the epidemiology of BS across different continents, newly developed instruments to assess damage in BS, studies highlighting the immunopathogenesis, genetics and epigenetic factors, histopathology of the pathergy lesion, clinical and imaging aspects of vascular involvement, and safety and efficacy of therapeutic agents including tocilizumab, apremilast and direct oral anticoagulants.
这篇综述重点介绍了 2021 年发表的关于白塞病（BS）不同方面的出版物，并提供了批判性的观点。这些出版物包括不同大陆 BS 流行病学的研究、新开发的评估 BS 损伤的工具、强调免疫发病机制、遗传学和表观遗传学因素、针刺病变的组织病理学、血管受累的临床和影像学方面以及包括托珠单抗、阿普米司特和直接口服抗凝剂在内的治疗药物的安全性和疗效的研究。
