Kottaras Steven, Stoikos Joshua, McKinlay Brandon J, Ludwa Izabella A, Josse Andrea R, Falk Bareket, Klentrou Panagiota
Department of Kinesiology, Brock University, St. Catharines, ON,Canada.
Centre for Bone and Muscle Health, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON,Canada.
Pediatr Exerc Sci. 2022 Jul 6;35(1):41-47. doi: 10.1123/pes.2022-0025. Print 2023 Feb 1.
This study examined differences in resting concentrations of markers of bone formation and resorption, and osteokines between female adolescent (12-16 y) swimmers, soccer players, and nonathletic controls. Resting, morning blood samples were obtained after an overnight fast from 20 swimmers, 20 soccer players, and 20 nonathletic controls, matched for age. carboxyl-terminal cross-linking telopeptide of type I collagen (CTX), amino-terminal propeptide of type I collagen (P1NP), total osteocalcin (OC), sclerostin, osteoprotegerin (OPG), and receptor activator of nuclear factor kappa B ligand (RANKL) were analyzed in serum. After controlling for percent body fat, there were no significant differences between swimmers and nonathletic controls in any of the measured markers. In contrast, soccer players had significantly higher P1NP (89.5 [25.6] ng·mL-1), OC (57.6 [22.9] ng·mL-1), and OPG (1052.5 [612.6] pg·mL-1) compared with both swimmers (P1NP: 66.5 [20.9] ng·mL-1; OC: 24.9 [12.5] ng·mL-1; OPG: 275.2 [83.8] pg·mL-1) and controls (P1NP: 58.5 [16.2] ng·mL-1; OC: 23.2 [11.9] ng·mL-1; OPG: 265.4 [97.6] pg·mL-1), with no differences in CTX, sclerostin, and RANKL. These results suggest that bone formation is higher in adolescent females engaged in high-impact sports like soccer compared with swimmers and controls.
本研究调查了青春期女性（12 - 16岁）游泳运动员、足球运动员和非运动对照组在静息状态下骨形成、骨吸收标志物以及骨因子水平的差异。在禁食过夜后，采集了20名游泳运动员、20名足球运动员和20名年龄匹配的非运动对照组的清晨静息血样。分析血清中的I型胶原羧基末端交联肽（CTX）、I型胶原氨基末端前肽（P1NP）、总骨钙素（OC）、硬化蛋白、骨保护素（OPG）和核因子κB受体活化因子配体（RANKL）。在控制体脂百分比后，游泳运动员和非运动对照组在任何测量标志物上均无显著差异。相比之下，与游泳运动员（P1NP：66.5 [20.9] ng·mL-1；OC：24.9 [12.5] ng·mL-1；OPG：275.2 [83.8] pg·mL-1）和对照组（P1NP：58.5 [16.2] ng·mL-1；OC：23.2 [11.9] ng·mL-1；OPG：265.4 [97.6] pg·mL-1）相比，足球运动员的P1NP（89.5 [25.6] ng·mL-1）、OC（57.6 [22.9] ng·mL-1）和OPG（1052.5 [612.6] pg·mL-1）显著更高，而CTX、硬化蛋白和RANKL无差异。这些结果表明，与游泳运动员和对照组相比，从事足球等高冲击力运动的青春期女性骨形成更高。
