Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Ophthalmology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Transl Vis Sci Technol. 2022 Jul 8;11(7):24. doi: 10.1167/tvst.11.7.24.
In acquiring images of the posterior eye, magnetic resonance imaging (MRI) provides low spatial resolution of the overall shape of the eye while optical coherence tomography (OCT) offers high spatial resolution of the limited range. Through the merger of the two devices, we attempted to acquire detailed anatomy of the posterior eye.
Optical and display distortions in OCT images were corrected using the Listing reduced eye model. The 3.0T orbital MRI images were placed on the three-dimensional coordinate system of the computer-aided design (CAD) program. Employing anterior scleral canal opening, visual axis, and scleral curvature as references, original and corrected OCT images were ported into the CAD application. The radii of curvature of the choroid-scleral interfaces (Rc values) of all original and corrected OCT images were compared to the MRI images.
Sixty-five eyes of 33 participants (45.58 ± 19.82 years) with a mean Rc of 12.94 ± 1.24 mm on axial MRI and 13.66 ± 2.81 mm on sagittal MRI were included. The uncorrected horizontal OCT (30.51 ± 9.34 mm) and the uncorrected vertical OCT (34.35 ± 18.09 mm) lengths differed significantly from the MRI Rc values (both P < 0.001). However, the mean Rc values of the corrected horizontal (12.50 ± 1.21 mm) and vertical (13.05 ± 1.98 mm) images did not differ significantly from the Rc values of the corresponding MRI planes (P = 0.065 and P = 0.198, respectively).
Features identifiable only on OCT and features only on MRI were successfully integrated into a unitary posterior eye.
Our CAD-based converging method may establish the collective anatomy of the posterior eye and the neural canal, beyond the range of the OCT.
在获取眼后图像时，磁共振成像（MRI）提供了眼睛整体形状的低空间分辨率，而光学相干断层扫描（OCT）则提供了有限范围内的高空间分辨率。通过合并这两种设备，我们试图获取眼后详细的解剖结构。
使用 Listing 简化眼模型校正 OCT 图像中的光学和显示失真。将 3.0T 眼眶 MRI 图像放置在计算机辅助设计（CAD）程序的三维坐标系上。以前巩膜管开口、视轴和巩膜曲率为参考，将原始和校正后的 OCT 图像导入 CAD 应用程序。比较所有原始和校正的 OCT 图像的脉络膜巩膜界面曲率半径（Rc 值）与 MRI 图像。
共纳入 33 名参与者（45.58 ± 19.82 岁）的 65 只眼，轴向 MRI 平均 Rc 值为 12.94 ± 1.24mm，矢状 MRI 平均 Rc 值为 13.66 ± 2.81mm。未校正的水平 OCT（30.51 ± 9.34mm）和未校正的垂直 OCT（34.35 ± 18.09mm）长度与 MRI Rc 值差异有统计学意义（均 P <0.001）。然而，校正后的水平（12.50 ± 1.21mm）和垂直（13.05 ± 1.98mm）图像的平均 Rc 值与相应 MRI 平面的 Rc 值差异无统计学意义（分别为 P = 0.065 和 P = 0.198）。
仅在 OCT 上可识别的特征和仅在 MRI 上可识别的特征成功地整合到一个统一的眼后单元中。
我们的 CAD 融合方法可能会建立一个超出 OCT 范围的后眼和神经管的整体解剖结构。
