Xu J, Li Y F, Dong Y, Zhao Z Y, Wen L Y, Zhang S Q, Lin D D, Zhou J, Liang S, Guo J G, Li S Z, Zhou X N
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Committee Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China.
Jiangxi Provincial Institute of Parasitic Diseases, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2022 Jul 5;34(3):223-229. doi: 10.16250/j.32.1374.2022111.
Preventive chemotherapy is one of the pivotal interventions for the control and elimination of schistosomiasis, which is effective to reduce the morbidity and prevalence of schistosomiasis. In order to promote the United Nations' sustainable development goals and the targets set for schistosomiasis control in the , WHO released the guideline on control and elimination of human schistosomiasis in 2022, with major evidence-based updates of the current preventive chemotherapy strategy for schistosomiasis. In China where great success has been achieved in schistosomiasis control, the preventive chemotherapy strategy for schistosomiasis has been updated several times during the past seven decades. This article reviews the evolution of the WHO guidelines on preventive chemotherapy and Chinese national preventive chemotherapy schemes, compares the current Chinese national preventive chemotherapy scheme and the recommendations for preventive chemotherapy proposed in the 2022 WHO guideline on control and elimination of human schistosomiasis, and proposes recommendations for preventive chemotherapy during the future implementation of the 2022 WHO guideline, so as to provide insights into schistosomiasis control among public health professionals engaging in healthcare foreign aid.
预防性化疗是控制和消除血吸虫病的关键干预措施之一，对降低血吸虫病的发病率和流行率有效。为推动联合国可持续发展目标以及为控制血吸虫病设定的具体目标，世界卫生组织于2022年发布了《控制和消除人体血吸虫病指南》，对当前血吸虫病预防性化疗策略进行了重大的循证更新。在中国，血吸虫病控制取得了巨大成功，血吸虫病预防性化疗策略在过去七十年里已多次更新。本文回顾了世界卫生组织预防性化疗指南和中国国家预防性化疗方案的演变，比较了当前中国国家预防性化疗方案与世界卫生组织2022年《控制和消除人体血吸虫病指南》中提出的预防性化疗建议，并针对未来实施世界卫生组织2022年指南时的预防性化疗提出建议，以便为从事医疗援外工作的公共卫生专业人员提供血吸虫病控制方面的见解。
