Instituto de Neurociencias "F. Oloriz", University of Granada, 18100 Granada, Spain.
Department of Psychology, Universidad de Almería, 04120 Almería, Spain.
Int J Environ Res Public Health. 2022 Jul 23;19(15):8964. doi: 10.3390/ijerph19158964.
Fibromyalgia and migraine frequently coexist. We aimed to compare the burden caused by fibromyalgia (FM), migraine (M) and comorbid fibromyalgia and migraine (FM + M) by assessing psychosocial variables and the use of healthcare resources. A survey was posted to the websites of different patients’ associations. It included sociodemographic data, the Patient Health Questionnaire-9, the Insomnia Severity Index, the EuroQOL-5D-5L and a questionnaire evaluating the use of healthcare resources during the past six months. In total, 139 FM patients, 169 M patients and 148 FM + M patients participated in the survey. Mean depression and insomnia scores were clinically relevant in every group and significantly higher in FM + M (16.3 ± 5.4 for depression, 18.5 ± 5.6 for insomnia) than in FM (14.3 ± 5.7 for depression, 16.8 ± 5.5 for insomnia) or M (11.7 ± 5.4 for depression, 13.1 ± 5.9 for depression), where p < 0.001 in both cases. Suicidal ideation was frequent in every group, but significantly more frequent in FM + M (63% vs. 45% in FM and 35% in M; p < 0.001). EQ-5D-5L (0.656 ± 0.1 in FM + M, 0.674 ± 0.1 in FM, 0.827 ± 0.1 in M, p < 0.001) and EQ-5D-5L VAS scores (38.2 ± 21.9 in FM + M, 45.6 ± 21.8 in FM, 63.5 ± 23.7 in M, p < 0.00) were lower than the reported mean population values and the lowest in FM + M. FM and FM + M used more healthcare resources than M. It is concluded that the psychosocial burden was high in the three samples. FM and FM + M had a more relevant impact on patients’ wellbeing and required more medical attention than M. The burden caused by FM + M was higher than in both individual diseases.
纤维肌痛症和偏头痛经常同时存在。我们旨在通过评估心理社会变量和医疗资源的使用来比较纤维肌痛症 (FM)、偏头痛 (M) 和共病纤维肌痛症和偏头痛 (FM + M) 造成的负担。一项调查被发布在不同患者协会的网站上。它包括社会人口统计学数据、患者健康问卷-9、失眠严重程度指数、欧洲五维健康量表 5 维度 5 水平和一个评估过去六个月医疗资源使用情况的问卷。共有 139 名纤维肌痛症患者、169 名偏头痛患者和 148 名纤维肌痛症和偏头痛共病患者参与了这项调查。每个组的抑郁和失眠评分都有临床意义，并且 FM + M 组（抑郁 16.3 ± 5.4，失眠 18.5 ± 5.6）显著高于 FM 组（抑郁 14.3 ± 5.7，失眠 16.8 ± 5.5）或 M 组（抑郁 11.7 ± 5.4，失眠 13.1 ± 5.9），在这两种情况下，p 值均＜0.001。每个组都有自杀意念，但 FM + M 组更常见（63% vs. FM 组的 45%和 M 组的 35%；p 值＜0.001）。EQ-5D-5L（FM + M 组为 0.656 ± 0.1，FM 组为 0.674 ± 0.1，M 组为 0.827 ± 0.1，p 值＜0.001）和 EQ-5D-5L VAS 评分（FM + M 组为 38.2 ± 21.9，FM 组为 45.6 ± 21.8，M 组为 63.5 ± 23.7，p 值＜0.001）低于报告的平均人群值，且在 FM + M 组中最低。纤维肌痛症和纤维肌痛症和偏头痛共病组比偏头痛组使用了更多的医疗资源。综上所述，这三个样本的心理社会负担都很高。纤维肌痛症和纤维肌痛症和偏头痛共病比偏头痛对患者的幸福感有更相关的影响，需要更多的医疗关注。纤维肌痛症和偏头痛共病造成的负担高于两种单独疾病。
