CHANGE Research Working Group, Facultad de Ciencias de la Salud, Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Perú.
Department of Cardiology Research, Torres de Salud National Research Center, Lima, Peru.
PLoS One. 2022 Sep 6;17(9):e0273949. doi: 10.1371/journal.pone.0273949. eCollection 2022.
Coronary disease (CD) is the main cause of mortality worldwide. Data about trends and geographical variation in CD mortality is available in some American countries. This information varies among countries since CD risk factors frequencies vary.
To describe the trend and geographical variation of coronary disease (CD) mortality in Peru, 2005-2017.
Analysis of secondary data of the Peruvian Ministry of Health's registry of deaths. We analyzed CD mortality. We described the absolute and relative frequency of deaths and age-standardized mortality rate (ASMR) by natural regions, departments, age, sex, and year. We also described the change of ASMR between two periods (2005-2010 vs. 2011-2017).
There were 64,721 CD deaths between 2005 and 2017 (4.12% among all deaths). The absolute frequency of CD deaths was 5,665 and 6,565 in 2005 and 2017, respectively. CD mortality was more frequent in men and older adults. The ASMR varied among natural regions, being higher in the Coast (19.61 per 100,000 inhabitants). The change between the two periods revealed that almost all departments reduced their ASMRs, except for Callao, Lambayeque, and Madre de Dios.
CD mortality has increased in Peru. Mortality was higher in men and older adults, and it varied among departments. More political efforts are needed to reduce these trends.
冠心病（CD）是全球主要的死亡原因。一些美国国家有冠心病死亡率趋势和地理差异的数据。由于冠心病危险因素的频率不同，这些信息因国家而异。
描述秘鲁 2005-2017 年冠心病死亡率的趋势和地理差异。
对秘鲁卫生部死亡登记处的二次数据进行分析。我们分析了冠心病死亡率。我们描述了按自然区域、部门、年龄、性别和年份划分的死亡绝对和相对频率以及年龄标准化死亡率（ASMR）。我们还描述了两个时期（2005-2010 年与 2011-2017 年）之间 ASMR 的变化。
2005 年至 2017 年间共有 64721 例冠心病死亡（占所有死亡人数的 4.12%）。冠心病死亡的绝对频率分别为 2005 年和 2017 年的 5665 和 6565 例。冠心病死亡率在男性和老年人中更为常见。ASMR 在自然区域之间存在差异，沿海地区（每 10 万人 19.61 人）最高。两个时期之间的变化表明，除了卡亚俄、兰巴耶克和马德雷德迪奥斯之外，几乎所有部门的 ASMR 都有所下降。
冠心病死亡率在秘鲁有所上升。男性和老年人的死亡率较高，各部门的死亡率也存在差异。需要做出更多的政治努力来降低这些趋势。
