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植物化学物质对人类肠道微生物群的影响,以实现平衡的生活。

The Impact of Plant Phytochemicals on the Gut Microbiota of Humans for a Balanced Life.

机构信息

Postgraduate Institute of Agriculture, University of Peradeniya, Peradeniya 20400, Sri Lanka.

Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.

出版信息

Int J Mol Sci. 2022 Jul 23;23(15):8124. doi: 10.3390/ijms23158124.

Abstract

The gastrointestinal tract of humans is a complex microbial ecosystem known as gut microbiota. The microbiota is involved in several critical physiological processes such as digestion, absorption, and related physiological functions and plays a crucial role in determining the host's health. The habitual consumption of specific dietary components can impact beyond their nutritional benefits, altering gut microbiota diversity and function and could manipulate health. Phytochemicals are non-nutrient biologically active plant components that can modify the composition of gut microflora through selective stimulation of proliferation or inhibition of certain microbial communities in the intestine. Plants secrete these components, and they accumulate in the cell wall and cell sap compartments (body) for their development and survival. These compounds have low bioavailability and long time-retention in the intestine due to their poor absorption, resulting in beneficial impacts on gut microbiota population. Feeding diets containing phytochemicals to humans and animals may offer a path to improve the gut microbiome resulting in improved performance and/or health and wellbeing. This review discusses the effects of phytochemicals on the modulation of the gut microbiota environment and the resultant benefits to humans; however, the effect of phytochemicals on the gut microbiota of animals is also covered, in brief.

摘要

人类的胃肠道是一个复杂的微生物生态系统,被称为肠道微生物群。微生物群参与了几个关键的生理过程,如消化、吸收和相关的生理功能,并在决定宿主健康方面起着至关重要的作用。习惯性地摄入特定的膳食成分,除了提供营养益处外,还可以通过选择性地刺激肠道中某些微生物群落的增殖或抑制来改变肠道微生物多样性和功能,从而影响健康。植物化学物质是具有生物活性的非营养植物成分,它们可以通过选择性地刺激肠道中某些微生物群落的增殖或抑制来改变肠道微生物群的组成。植物分泌这些成分,并将它们积累在细胞壁和细胞液隔室(体)中,以促进其发育和生存。由于吸收不良,这些化合物在肠道中的生物利用度低,保留时间长,因此对肠道微生物群的有益影响。给人类和动物喂食含有植物化学物质的饮食可能是改善肠道微生物组的一种途径,从而提高性能和/或健康和福祉。本文综述了植物化学物质对肠道微生物群环境调节的影响及其对人类的益处;然而,也简要讨论了植物化学物质对动物肠道微生物群的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd56/9332059/61998912e213/ijms-23-08124-g001.jpg

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