Sikakulya F K, Munyambalu D K, Mambo S B, Mutsunga A K, Djuma S F, Djuna P A, Ndiwelubula E, Ngavo W A, Sahika S M, Kumbakulu Patrick Kumbowi, Adelard Kalima Nzanzu, Shindano T A
Department of General Surgery, Kampala International University, Western Campus, Bushenyi, Uganda.
Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo.
Infect Prev Pract. 2022 Jun 24;4(3):100226. doi: 10.1016/j.infpip.2022.100226. eCollection 2022 Sep.
In low resource settings in sub-Saharan Africa healthcare workers (HCW) have a high risk of contracting hepatitis B infection. Vaccination of HCWs is to protect them from acquisition of hepatitis B from patients.
To evaluate the hepatitis B virus (HBV) serological and vaccination status of HCWs in the Butembo Antenna in the Eastern Democratic Republic of Congo (DR Congo) and to investigate the factors influencing hepatitis screening and vaccination.
A cross-sectional study using a structured questionnaire was carried out from 1 to 30 April 2021 among consenting HCWs in Butembo (≥18 years of age). Data was analysed using SPSS version 23.
Of 373 participants, 178 (47.7%) had already been screened for HBV. Screening was more likely for HCWs in a rural or publicly owned facility (<0.05). A total of 25 (6.7%) HCWs were fully vaccinated against HBV; the factors associated with full vaccination were: prior screening for HBV (odds ratio: 9.03 (2.51-38.61), <0.0001), prior knowledge of the value of post-exposure prophylaxis (odds ratio 12.9 (2.89-80.44), =0.0004), prior knowledge of hepatitis B vaccine benefits (adjusted odds ratio: 4.54 (1.66-13.05), =0.002) and prior exposure to hepatitis B infection (adjusted odds ratio: 2.61 (1.08-6.39), =0.039).
Screening and vaccination rates of HCWs for HBV are extremely low, and not high enough to prevent the spread of this serious illness and its complications. There is a dire need to increase vaccination rates among HCWs in Eastern DR Congo. The DRC government should issue vaccination against HBV as a recommendation at the national level.
在撒哈拉以南非洲的资源匮乏地区，医护人员感染乙型肝炎的风险很高。医护人员接种疫苗是为了保护他们免受患者感染乙型肝炎。
评估刚果民主共和国（DR刚果）东部布滕博天线区医护人员的乙型肝炎病毒（HBV）血清学和疫苗接种状况，并调查影响肝炎筛查和疫苗接种的因素。
2021年4月1日至30日，对布滕博地区（≥18岁）同意参与的医护人员进行了一项使用结构化问卷的横断面研究。使用SPSS 23版软件进行数据分析。
在373名参与者中，178人（47.7%）已经接受过HBV筛查。在农村或公立机构工作的医护人员接受筛查的可能性更大（<0.05）。共有25名（6.7%）医护人员完成了HBV全程疫苗接种；与全程疫苗接种相关的因素有：既往接受过HBV筛查（比值比：9.03（2.51-38.61），<0.0001）、既往了解暴露后预防的价值（比值比1 .9（2.89-80.44），=0.0004）、既往了解乙型肝炎疫苗的益处（调整后比值比：4.54（1.66-13.05），=0.002）以及既往接触过乙型肝炎感染（调整后比值比：2.61（1.08-6.39），=0.039）。
医护人员的HBV筛查和疫苗接种率极低，不足以预防这种严重疾病及其并发症的传播。刚果民主共和国东部迫切需要提高医护人员的疫苗接种率。刚果民主共和国政府应在国家层面将HBV疫苗接种作为一项建议发布。
