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乳腺癌转移至甲状腺:非常规转移部位。

Breast cancer to thyroid gland: An unconventional metastatic site.

机构信息

Department of Medical Oncology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Department of Pathology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

出版信息

J Cancer Res Ther. 2022 Apr-Jun;18(3):788-791. doi: 10.4103/jcrt.JCRT_561_20.

DOI:10.4103/jcrt.JCRT_561_20
PMID:35900558
Abstract

Thyroid gland blood supply is rich but it is not an open area for metastasis. Only 1%-3% of the neoplastic lesions seen in the thyroid are of extrathyroidal origin. Thyroid, lung, bone, lymph node metastasis were detected at the time of diagnosis in a 78-year-old woman with metastatic breast cancer. Control imaging was performed 3 months after hormone therapy was started. All lesions were regressed except thyroid lesion and neck lymph. Tru-cut biopsy was performed to the lesion in the thyroid. The result is consistent with breast cancer metastasis. With this breast cancer metastasis to thyroid case, we want to emphasize the differential diagnosis of neoplastic lesions in the thyroid is important in those diagnosed with malignancy. If there is clinical suspicion after a nondiagnostic thyroid sampling, repeated biopsies should be performed.

摘要

甲状腺血供丰富,但并非转移的开放区域。在甲状腺中见到的肿瘤病变中,仅有 1%-3%为甲状腺外起源。一名 78 岁患有转移性乳腺癌的女性在诊断时发现甲状腺、肺、骨、淋巴结转移。开始激素治疗后 3 个月进行了对照影像学检查。除甲状腺病变和颈部淋巴结外,所有病变均消退。对甲状腺的病变进行了 tru-cut 活检。结果与乳腺癌转移一致。通过这个甲状腺转移癌的病例,我们想强调在诊断为恶性肿瘤的患者中,对甲状腺内肿瘤病变进行鉴别诊断很重要。如果在非诊断性甲状腺取样后存在临床怀疑,应重复进行活检。

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引用本文的文献

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Int J Surg Case Rep. 2025 Jul;132:111480. doi: 10.1016/j.ijscr.2025.111480. Epub 2025 Jun 7.
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Thyroid Metastasis from Primary Breast Cancer.原发性乳腺癌的甲状腺转移
J Clin Med. 2023 Apr 4;12(7):2709. doi: 10.3390/jcm12072709.