Department of Oral Medicine and Radiology, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India.
Department of Pathology, Rural Medical College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India.
J Cancer Res Ther. 2022 Apr-Jun;18(3):849-852. doi: 10.4103/jcrt.JCRT_1123_20.
Metastatic malignant melanoma (MMM) of the oral cavity is extremely rare which generally presents in the setting of disseminated disease and have extremely poor prognosis. The most common site for MMM in the oral cavity is tongue followed by buccal mucosa for soft-tissue lesions and posterior mandible for bone involving lesions. Primary tumor sites of oral MMM are usually cutaneous lesions of the trunk, head and neck, limbs, and nasal septum mucosa. Patients bearing this diagnosis face median survival time of approximately 9 months with a probability of surviving 5 years after the initial presentation is <5%; hence, an early detection and treatment for the primary and metastatic lesion is crucial. Here, we present an unusual case of MMM of oral cavity involving gingiva and alveolar bone of the mandibular anterior region metastasizing from a primary lesion on the foot.
口腔转移性恶性黑色素瘤（MMM）极为罕见，通常发生在疾病扩散的情况下，预后极差。口腔 MMM 最常见的部位是舌，其次是颊黏膜的软组织病变和下颌骨的骨受累病变。口腔 MMM 的原发肿瘤部位通常是躯干、头颈部、四肢和鼻中隔黏膜的皮肤病变。患有这种诊断的患者中位生存时间约为 9 个月，初始表现后 5 年的生存率<5%；因此，早期发现和治疗原发和转移病灶至关重要。在这里，我们报告了一个不寻常的口腔 MMM 病例，涉及下颌前区的牙龈和牙槽骨，由足部的原发性病变转移而来。
