Carr R T, Xiao J
Department of Chemical Engineering, University of New Hampshire, Durham, USA.
Microcirculation. 1995 Dec;2(4):345-53. doi: 10.3109/10739689509148278.
A new model of plasma skimming in vascular trees that includes the history of disturbances at previous bifurcations is developed. The model calculates the shift in the red blood cell concentration profile by mapping streamlines through the junction; it then computes the dissipation of that disturbance through random collisions among the cells. A numerical solution of this model is compared to experimental data on plasma skimming in serial bifurcations. Numerical values of symmetry recovery lengths downstream of the bifurcation are calculated using the model. Comparison of the computed symmetry recovery lengths with anatomical measurements in hamster cremaster muscle indicate that asymmetries in red blood cell concentration profiles are important in vessels with diameters below 55 microns.
开发了一种血管树中血浆撇取的新模型，该模型考虑了先前分支处的扰动历史。该模型通过绘制穿过连接处的流线来计算红细胞浓度分布的变化；然后通过细胞间的随机碰撞计算该扰动的消散。将该模型的数值解与串联分支中血浆撇取的实验数据进行比较。使用该模型计算分支下游对称恢复长度的数值。将计算出的对称恢复长度与仓鼠提睾肌的解剖测量结果进行比较，结果表明，红细胞浓度分布的不对称性在直径小于55微米的血管中很重要。
