Huerkamp M J
Division of Animal Resources, Emory University School of Medicine, Atlanta, GA 30322.
Lab Anim Sci. 1993 Feb;43(1):86-90.
Studies using rats that were naturally infested with Syphacia muris and kept in forced-air, individually ventilated cages showed that ivermectin given orally at a dose of 2 mg/kg for three treatments at 7- or 9-day intervals was eradicative. Paired ivermectin treatments given at 7- or 9-day intervals were ineffective in eliminating parasitism. Pinworm eggs persisted on the perianal region of rats for up to 17 days and eggs were also present in soiled contact bedding within cages and on surfaces within the animal room. Anal tapes as a diagnostic test had 88% sensitivity in detecting pinworms.
对自然感染鼠管状线虫的大鼠进行的研究显示，将大鼠置于强制通风、独立通风的笼子中，口服剂量为2mg/kg的伊维菌素，每隔7天或9天进行三次治疗，可根除感染。每隔7天或9天进行的伊维菌素配对治疗在消除寄生虫感染方面无效。蛲虫卵在大鼠肛周区域可存活长达17天，笼子内被污染的接触垫料和动物房内的表面也有虫卵。肛门胶带作为一种诊断测试，在检测蛲虫方面具有88%的灵敏度。
