National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India.
National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India; Department of Plant Sciences, University of Hyderabad, Hyderabad 500046, Telangana, India.
Trends Plant Sci. 2022 Dec;27(12):1242-1252. doi: 10.1016/j.tplants.2022.07.003. Epub 2022 Jul 25.
Viruses are acellular pathogens that cause severe infections in plants, resulting in worldwide crop losses every year. The lack of chemical agents to control viral diseases exacerbates the situation. Thus, to devise proper management strategies, it is important that the defense mechanisms of plants against viruses are understood. Resistance (R) genes regulate plant defense against invading pathogens by eliciting a hypersensitive response (HR). Compatible interaction between plant R gene and viral avirulence (Avr) protein activates the necrotic cell death response at the site of infection, resulting in the cessation of disease. Here, we review different aspects of R gene-mediated dominant resistance against plant viruses in dicotyledonous plants and possible ways for developing crops with better disease resistance.
病毒是无细胞病原体，可导致植物严重感染，每年造成全球作物损失。缺乏控制病毒性疾病的化学制剂使情况恶化。因此，为了制定适当的管理策略，了解植物对病毒的防御机制很重要。抗性（R）基因通过引发过敏反应（HR）来调节植物对入侵病原体的防御。植物 R 基因与病毒无毒（Avr）蛋白之间的兼容相互作用会激活感染部位的坏死细胞死亡反应，从而停止疾病的发生。在这里，我们回顾了双子叶植物中 R 基因介导的对植物病毒的显性抗性的不同方面，以及开发具有更好抗病性的作物的可能途径。
