Huang Kuan-Wei, Lin Pao-Yen, Lee Yu, Huang Yu-Chi, Hung Chi-Fa, Lee Sheng-Yu, Chen Chih-Ken, Wang Liang-Jen
Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Institute for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Psychiatry Investig. 2022 Jul;19(7):511-518. doi: 10.30773/pi.2021.0322. Epub 2022 Jul 21.
The Schizophrenia Cognition Rating Scale (SCoRS) is an interview-based assessment tool for evaluating the cognitive deficit and daily functioning of patients with schizophrenia.
Sixty-eight patients with schizophrenia and 68 age- and sex-matched healthy individuals were recruited to validate the Chinese version of SCoRS in this study. All participants underwent cognitive assessment using the SCoRS, which was verified by the Brief Assessment of Cognition in Schizophrenia (BACS), and the UCSD Performance-based Skills Assessment, Brief Version (UPSA-B). Patients with schizophrenia were additionally assessed using the Positive and Negative Syndrome Scale (PANSS).
SCoRS ratings reported by patients (SCoRS-S), those reported by the interviewer (SCoRS-I), and SCoRS global scores (SCoRS-G) showed significant correlation with all subscales of the BACS and the UPSA-B. On receiver operating characteristic curve analysis, SCoRS-S, SCoRS-I, and SCoRS-G significantly differentiated patients with schizophrenia from healthy controls. Moreover, SCoRS-S and SCoRS-I ratings showed positive correlation with the negative symptoms and general symptoms of PANSS.
The Chinese version of SCoRS showed good discriminant, concurrent, and external validity, suggesting that it is a useful and convenient tool for assessment of cognitive function among Mandarin-speaking patients with schizophrenia in clinical practice.
精神分裂症认知评定量表(SCoRS)是一种基于访谈的评估工具,用于评估精神分裂症患者的认知缺陷和日常功能。
本研究招募了68例精神分裂症患者和68例年龄及性别匹配的健康个体,以验证SCoRS中文版。所有参与者均使用SCoRS进行认知评估,该评估由精神分裂症认知简短评估量表(BACS)和加利福尼亚大学圣地亚哥分校基于表现的技能评估简版(UPSA-B)进行验证。另外,使用阳性和阴性症状量表(PANSS)对精神分裂症患者进行评估。
患者报告的SCoRS评分(SCoRS-S)、访谈者报告的评分(SCoRS-I)和SCoRS总体评分(SCoRS-G)与BACS和UPSA-B的所有子量表均显示出显著相关性。在接受者操作特征曲线分析中,SCoRS-S、SCoRS-I和SCoRS-G能够显著区分精神分裂症患者与健康对照。此外,SCoRS-S和SCoRS-I评分与PANSS的阴性症状和一般症状呈正相关。
SCoRS中文版显示出良好的区分效度、同时效度和外部效度,表明它是临床实践中评估说普通话的精神分裂症患者认知功能的一种有用且便捷的工具。